Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index

Yu-Qiang Zuo,1 Zhi-Hong Gao,1 Yu-Ling Yin,1 Xu Yang,1 Ping-Yong Feng2 1Department of Health Physical Examination Center, The 2nd Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Imaging Center, The 2nd Hospital of Hebei Medical University, Shijiazhuang,...

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Autores principales:	Zuo YQ, Gao ZH, Yin YL, Yang X, Feng PY
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	cardiometabolic index hyperuricemia visceral adiposity index lipid accumulation product Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/5463c2187e21435088983bd85458705a
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spelling	oai:doaj.org-article:5463c2187e21435088983bd85458705a2021-11-23T18:43:01ZAssociation Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index1178-7074https://doaj.org/article/5463c2187e21435088983bd85458705a2021-11-01T00:00:00Zhttps://www.dovepress.com/association-between-the-cardiometabolic-index-and-hyperuricemia-in-an--peer-reviewed-fulltext-article-IJGMhttps://doaj.org/toc/1178-7074Yu-Qiang Zuo,1 Zhi-Hong Gao,1 Yu-Ling Yin,1 Xu Yang,1 Ping-Yong Feng2 1Department of Health Physical Examination Center, The 2nd Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Imaging Center, The 2nd Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Ping-Yong Feng Email xjfpy@163.comBackground and Purpose: The association between the cardiometabolic index (CMI) and hyperuricemia was investigated to provide theoretical support for the management of hyperuricemia in an asymptomatic population with normal body mass index (BMI).Methods: A cross-sectional study was carried out among 374 asymptomatic adults with normal BMI. Traditional anthropometric indices and CMI were calculated. Anthropometric indices were divided into four quartiles and multivariate logistic analysis was used to analyze the association between these indices and hyperuricemia. Receiver operating characteristic (ROC) curves and area under the curve (AUC) were used to evaluate the power of the indices to predict hyperuricemia values. The DeLong test was used to compare the AUC of different anthropometric indices.Results: After adjusting for confounding variables, the CMI exhibited a stronger association with hyperuricemia than other anthropometric indices. The odds ratio (OR) for hyperuricemia in the highest quartile of the CMI was 16.674 (confidence interval [CI]=4.424– 62.846). The AUC of the CMI was 0.777 (95% CI=0.719– 0.835, p< 0.001), which was higher than the values for other anthropometric indices. The differences in AUC between the CMI and other indices were statistically significant; the optimal cutoff value of the CMI was 0.655, with sensitivity of 57.1% and specificity of 84.2%.Conclusion: The CMI, which combines waist circumference, height and blood lipid parameters, was more strongly associated with hyperuricemia than other anthropometric indices in asymptomatic population with normal BMI. The CMI may serve as a potential monitoring indicator for hyperuricemia management in asymptomatic populations with normal BMI.Keywords: cardiometabolic index, hyperuricemia, visceral adiposity index, lipid accumulation productZuo YQGao ZHYin YLYang XFeng PYDove Medical Pressarticlecardiometabolic indexhyperuricemiavisceral adiposity indexlipid accumulation productMedicine (General)R5-920ENInternational Journal of General Medicine, Vol Volume 14, Pp 8603-8610 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiometabolic index hyperuricemia visceral adiposity index lipid accumulation product Medicine (General) R5-920
spellingShingle	cardiometabolic index hyperuricemia visceral adiposity index lipid accumulation product Medicine (General) R5-920 Zuo YQ Gao ZH Yin YL Yang X Feng PY Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index
description	Yu-Qiang Zuo,1 Zhi-Hong Gao,1 Yu-Ling Yin,1 Xu Yang,1 Ping-Yong Feng2 1Department of Health Physical Examination Center, The 2nd Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Imaging Center, The 2nd Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Ping-Yong Feng Email xjfpy@163.comBackground and Purpose: The association between the cardiometabolic index (CMI) and hyperuricemia was investigated to provide theoretical support for the management of hyperuricemia in an asymptomatic population with normal body mass index (BMI).Methods: A cross-sectional study was carried out among 374 asymptomatic adults with normal BMI. Traditional anthropometric indices and CMI were calculated. Anthropometric indices were divided into four quartiles and multivariate logistic analysis was used to analyze the association between these indices and hyperuricemia. Receiver operating characteristic (ROC) curves and area under the curve (AUC) were used to evaluate the power of the indices to predict hyperuricemia values. The DeLong test was used to compare the AUC of different anthropometric indices.Results: After adjusting for confounding variables, the CMI exhibited a stronger association with hyperuricemia than other anthropometric indices. The odds ratio (OR) for hyperuricemia in the highest quartile of the CMI was 16.674 (confidence interval [CI]=4.424– 62.846). The AUC of the CMI was 0.777 (95% CI=0.719– 0.835, p< 0.001), which was higher than the values for other anthropometric indices. The differences in AUC between the CMI and other indices were statistically significant; the optimal cutoff value of the CMI was 0.655, with sensitivity of 57.1% and specificity of 84.2%.Conclusion: The CMI, which combines waist circumference, height and blood lipid parameters, was more strongly associated with hyperuricemia than other anthropometric indices in asymptomatic population with normal BMI. The CMI may serve as a potential monitoring indicator for hyperuricemia management in asymptomatic populations with normal BMI.Keywords: cardiometabolic index, hyperuricemia, visceral adiposity index, lipid accumulation product
format	article
author	Zuo YQ Gao ZH Yin YL Yang X Feng PY
author_facet	Zuo YQ Gao ZH Yin YL Yang X Feng PY
author_sort	Zuo YQ
title	Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index
title_short	Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index
title_full	Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index
title_fullStr	Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index
title_full_unstemmed	Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index
title_sort	association between the cardiometabolic index and hyperuricemia in an asymptomatic population with normal body mass index
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/5463c2187e21435088983bd85458705a
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Association Between the Cardiometabolic Index and Hyperuricemia in an Asymptomatic Population with Normal Body Mass Index

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