Gene-based tests of association.
Genome-wide association studies (GWAS) are now used routinely to identify SNPs associated with complex human phenotypes. In several cases, multiple variants within a gene contribute independently to disease risk. Here we introduce a novel Gene-Wide Significance (GWiS) test that uses greedy Bayesian...
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Autores principales: | Hailiang Huang, Pritam Chanda, Alvaro Alonso, Joel S Bader, Dan E Arking |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/54690885618f4c6b97de466b5a371a4b |
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