Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances susceptibility to viral infection.
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Nature Portfolio
2018
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oai:doaj.org-article:547b377f526943aa911360a9ae058cac2021-12-02T15:33:37ZVibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity10.1038/s41467-018-04075-12041-1723https://doaj.org/article/547b377f526943aa911360a9ae058cac2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04075-1https://doaj.org/toc/2041-1723Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances susceptibility to viral infection.Wooseong LeeSeung-Hoon LeeMinwoo KimJae-Su MoonGeon-Woo KimHae-Gwang JungIn Hwang KimJi Eun OhHi Eun JungHeung Kyu LeeKeun Bon KuDae-Gyun AhnSeong-Jun KimKun-Soo KimJong-Won OhNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
institution |
DOAJ |
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DOAJ |
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Science Q |
spellingShingle |
Science Q Wooseong Lee Seung-Hoon Lee Minwoo Kim Jae-Su Moon Geon-Woo Kim Hae-Gwang Jung In Hwang Kim Ji Eun Oh Hi Eun Jung Heung Kyu Lee Keun Bon Ku Dae-Gyun Ahn Seong-Jun Kim Kun-Soo Kim Jong-Won Oh Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity |
description |
Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances susceptibility to viral infection. |
format |
article |
author |
Wooseong Lee Seung-Hoon Lee Minwoo Kim Jae-Su Moon Geon-Woo Kim Hae-Gwang Jung In Hwang Kim Ji Eun Oh Hi Eun Jung Heung Kyu Lee Keun Bon Ku Dae-Gyun Ahn Seong-Jun Kim Kun-Soo Kim Jong-Won Oh |
author_facet |
Wooseong Lee Seung-Hoon Lee Minwoo Kim Jae-Su Moon Geon-Woo Kim Hae-Gwang Jung In Hwang Kim Ji Eun Oh Hi Eun Jung Heung Kyu Lee Keun Bon Ku Dae-Gyun Ahn Seong-Jun Kim Kun-Soo Kim Jong-Won Oh |
author_sort |
Wooseong Lee |
title |
Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity |
title_short |
Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity |
title_full |
Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity |
title_fullStr |
Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity |
title_full_unstemmed |
Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity |
title_sort |
vibrio vulnificus quorum-sensing molecule cyclo(phe-pro) inhibits rig-i-mediated antiviral innate immunity |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/547b377f526943aa911360a9ae058cac |
work_keys_str_mv |
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