Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity

Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances susceptibility to viral infection.

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Autores principales: Wooseong Lee, Seung-Hoon Lee, Minwoo Kim, Jae-Su Moon, Geon-Woo Kim, Hae-Gwang Jung, In Hwang Kim, Ji Eun Oh, Hi Eun Jung, Heung Kyu Lee, Keun Bon Ku, Dae-Gyun Ahn, Seong-Jun Kim, Kun-Soo Kim, Jong-Won Oh
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/547b377f526943aa911360a9ae058cac
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spelling oai:doaj.org-article:547b377f526943aa911360a9ae058cac2021-12-02T15:33:37ZVibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity10.1038/s41467-018-04075-12041-1723https://doaj.org/article/547b377f526943aa911360a9ae058cac2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04075-1https://doaj.org/toc/2041-1723Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances susceptibility to viral infection.Wooseong LeeSeung-Hoon LeeMinwoo KimJae-Su MoonGeon-Woo KimHae-Gwang JungIn Hwang KimJi Eun OhHi Eun JungHeung Kyu LeeKeun Bon KuDae-Gyun AhnSeong-Jun KimKun-Soo KimJong-Won OhNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wooseong Lee
Seung-Hoon Lee
Minwoo Kim
Jae-Su Moon
Geon-Woo Kim
Hae-Gwang Jung
In Hwang Kim
Ji Eun Oh
Hi Eun Jung
Heung Kyu Lee
Keun Bon Ku
Dae-Gyun Ahn
Seong-Jun Kim
Kun-Soo Kim
Jong-Won Oh
Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
description Quorum sensing signaling molecules are known to be critical determinants in bacterial pathogenesis. Here the authors show the quorum sensing molecule cFP from Vibrio vulnificus inhibits the RIG-I mediated antiviral interferon response and enhances susceptibility to viral infection.
format article
author Wooseong Lee
Seung-Hoon Lee
Minwoo Kim
Jae-Su Moon
Geon-Woo Kim
Hae-Gwang Jung
In Hwang Kim
Ji Eun Oh
Hi Eun Jung
Heung Kyu Lee
Keun Bon Ku
Dae-Gyun Ahn
Seong-Jun Kim
Kun-Soo Kim
Jong-Won Oh
author_facet Wooseong Lee
Seung-Hoon Lee
Minwoo Kim
Jae-Su Moon
Geon-Woo Kim
Hae-Gwang Jung
In Hwang Kim
Ji Eun Oh
Hi Eun Jung
Heung Kyu Lee
Keun Bon Ku
Dae-Gyun Ahn
Seong-Jun Kim
Kun-Soo Kim
Jong-Won Oh
author_sort Wooseong Lee
title Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
title_short Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
title_full Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
title_fullStr Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
title_full_unstemmed Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
title_sort vibrio vulnificus quorum-sensing molecule cyclo(phe-pro) inhibits rig-i-mediated antiviral innate immunity
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/547b377f526943aa911360a9ae058cac
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