Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces

Abstract VOCs (volatile organic compounds) are increasingly wished to be used in diagnosis of diseases. They present strategic advantages, when compared to classical methods used, such as simplicity and current availability of performant non-invasive sample collection methods/systems. However, stand...

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Autores principales:	Ileana Andreea Ratiu, Radik Mametov, Tomasz Ligor, Bogusław Buszewski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/548711760f424381b4283b4a193789dc
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spelling	oai:doaj.org-article:548711760f424381b4283b4a193789dc2021-12-02T15:15:23ZMicro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces10.1038/s41598-021-98279-z2045-2322https://doaj.org/article/548711760f424381b4283b4a193789dc2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98279-zhttps://doaj.org/toc/2045-2322Abstract VOCs (volatile organic compounds) are increasingly wished to be used in diagnosis of diseases. They present strategic advantages, when compared to classical methods used, such as simplicity and current availability of performant non-invasive sample collection methods/systems. However, standardized sampling methods are required in order to achieve reproducible results. In the current study we developed a method to be used for feces sampling using a Micro-Chamber/Thermal Extractor (µ-CTE). Design Expert software (with Box–Behnken design) was used to predict the solutions. Therefore, by using the simulation experimental plan that was further experimentally verified, extraction time of 19.6 min, at extraction temperature of 30.6 °C by using a flow rate of 48.7 mL/min provided the higher response. The developed method was validated by using correlation tests and Network analysis, which both proved the validity of the developed model.Ileana Andreea RatiuRadik MametovTomasz LigorBogusław BuszewskiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ileana Andreea Ratiu Radik Mametov Tomasz Ligor Bogusław Buszewski Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
description	Abstract VOCs (volatile organic compounds) are increasingly wished to be used in diagnosis of diseases. They present strategic advantages, when compared to classical methods used, such as simplicity and current availability of performant non-invasive sample collection methods/systems. However, standardized sampling methods are required in order to achieve reproducible results. In the current study we developed a method to be used for feces sampling using a Micro-Chamber/Thermal Extractor (µ-CTE). Design Expert software (with Box–Behnken design) was used to predict the solutions. Therefore, by using the simulation experimental plan that was further experimentally verified, extraction time of 19.6 min, at extraction temperature of 30.6 °C by using a flow rate of 48.7 mL/min provided the higher response. The developed method was validated by using correlation tests and Network analysis, which both proved the validity of the developed model.
format	article
author	Ileana Andreea Ratiu Radik Mametov Tomasz Ligor Bogusław Buszewski
author_facet	Ileana Andreea Ratiu Radik Mametov Tomasz Ligor Bogusław Buszewski
author_sort	Ileana Andreea Ratiu
title	Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
title_short	Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
title_full	Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
title_fullStr	Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
title_full_unstemmed	Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces
title_sort	micro-chamber/thermal extractor (µ-cte) as a new sampling system for vocs emitted by feces
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/548711760f424381b4283b4a193789dc
work_keys_str_mv	AT ileanaandreearatiu microchamberthermalextractorμcteasanewsamplingsystemforvocsemittedbyfeces AT radikmametov microchamberthermalextractorμcteasanewsamplingsystemforvocsemittedbyfeces AT tomaszligor microchamberthermalextractorμcteasanewsamplingsystemforvocsemittedbyfeces AT bogusławbuszewski microchamberthermalextractorμcteasanewsamplingsystemforvocsemittedbyfeces
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Micro-Chamber/Thermal Extractor (µ-CTE) as a new sampling system for VOCs emitted by feces

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