Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers

The COVID-19 pandemic is placing a heavy burden on healthcare systems worldwide with the risk that acute cardiovascular diseases are treated too late. The present study aims to analyze patients with acute coronary syndrome in the current pandemic. A total of 966 patients (2019 <i>n</i> =...

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Autores principales:	Dennis Eckner, Eva M. Hofmann, Fadil Ademaj, Kristinko Martinovic, Ferdinand Vogt, Peter Moritz Becher, Benedikt Schrage, Dirk Westermann, Matthias Pauschinger
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	COVID-19 pandemic acute coronary syndrome pain to first medical contact age distribution subacute myocardial infarction Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/54929fd9642c46cfaedeec85715685df
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spelling	oai:doaj.org-article:54929fd9642c46cfaedeec85715685df2021-11-25T18:00:18ZDifferences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers10.3390/jcdd81101452308-3425https://doaj.org/article/54929fd9642c46cfaedeec85715685df2021-10-01T00:00:00Zhttps://www.mdpi.com/2308-3425/8/11/145https://doaj.org/toc/2308-3425The COVID-19 pandemic is placing a heavy burden on healthcare systems worldwide with the risk that acute cardiovascular diseases are treated too late. The present study aims to analyze patients with acute coronary syndrome in the current pandemic. A total of 966 patients (2019 <i>n</i> = 463, 2020 <i>n</i> = 503) can be evaluated. A comparison of patient care during and before the COVID-19 pandemic was made in terms of patient characteristics and pre- and in-hospital processes. Another aim is to show how many patients seek clinical care at a late stage of the disease. After Lockdown in Germany at week 12, 2020, there was a significant decrease in patients with an acute coronary syndrome (ACS), significant for STEMI cases in the first weeks after Lockdown (calendar week 13–16 2019 <i>n</i> = 43, 2020 <i>n</i> = 30; <i>p</i> = 0.02). The time from pain to first medical contact (time to FMC) is significantly extended during Lockdown, while internal clinical processes are unchanged. The rate of subacute myocardial infarction is numerically, but not significantly increased in calendar weeks 15, 2020 (<i>p</i> = 0.40) and 16 (<i>p</i> = 0,19). In addition, elderly patients avoid treatment for multifactorial reasons, and the longer overall pain to FMC may impact long-term mortality.Dennis EcknerEva M. HofmannFadil AdemajKristinko MartinovicFerdinand VogtPeter Moritz BecherBenedikt SchrageDirk WestermannMatthias PauschingerMDPI AGarticleCOVID-19 pandemicacute coronary syndromepain to first medical contactage distributionsubacute myocardial infarctionDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of Cardiovascular Development and Disease, Vol 8, Iss 145, p 145 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 pandemic acute coronary syndrome pain to first medical contact age distribution subacute myocardial infarction Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	COVID-19 pandemic acute coronary syndrome pain to first medical contact age distribution subacute myocardial infarction Diseases of the circulatory (Cardiovascular) system RC666-701 Dennis Eckner Eva M. Hofmann Fadil Ademaj Kristinko Martinovic Ferdinand Vogt Peter Moritz Becher Benedikt Schrage Dirk Westermann Matthias Pauschinger Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers
description	The COVID-19 pandemic is placing a heavy burden on healthcare systems worldwide with the risk that acute cardiovascular diseases are treated too late. The present study aims to analyze patients with acute coronary syndrome in the current pandemic. A total of 966 patients (2019 <i>n</i> = 463, 2020 <i>n</i> = 503) can be evaluated. A comparison of patient care during and before the COVID-19 pandemic was made in terms of patient characteristics and pre- and in-hospital processes. Another aim is to show how many patients seek clinical care at a late stage of the disease. After Lockdown in Germany at week 12, 2020, there was a significant decrease in patients with an acute coronary syndrome (ACS), significant for STEMI cases in the first weeks after Lockdown (calendar week 13–16 2019 <i>n</i> = 43, 2020 <i>n</i> = 30; <i>p</i> = 0.02). The time from pain to first medical contact (time to FMC) is significantly extended during Lockdown, while internal clinical processes are unchanged. The rate of subacute myocardial infarction is numerically, but not significantly increased in calendar weeks 15, 2020 (<i>p</i> = 0.40) and 16 (<i>p</i> = 0,19). In addition, elderly patients avoid treatment for multifactorial reasons, and the longer overall pain to FMC may impact long-term mortality.
format	article
author	Dennis Eckner Eva M. Hofmann Fadil Ademaj Kristinko Martinovic Ferdinand Vogt Peter Moritz Becher Benedikt Schrage Dirk Westermann Matthias Pauschinger
author_facet	Dennis Eckner Eva M. Hofmann Fadil Ademaj Kristinko Martinovic Ferdinand Vogt Peter Moritz Becher Benedikt Schrage Dirk Westermann Matthias Pauschinger
author_sort	Dennis Eckner
title	Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers
title_short	Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers
title_full	Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers
title_fullStr	Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers
title_full_unstemmed	Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers
title_sort	differences in the treatment of acute coronary syndrome in the pre-covid and covid era: an analysis from two german high-volume centers
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/54929fd9642c46cfaedeec85715685df
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Differences in the Treatment of Acute Coronary Syndrome in the Pre-COVID and COVID Era: An Analysis from Two German High-Volume Centers

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