Optimal management of coronary artery disease in cancer patients

Owing to early diagnosis and rapid development of treatments for cancers, the five-year survival rate of all cancer types has markedly improved worldwide. Over time, however, there has been an increase in the number of cancer patients who develop coronary artery disease (CAD) due to different causes...

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Autores principales: Xue-Jie Han, Jian-Qiang Li, Zulfiia Khannanova, Yue Li
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Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2019
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Acceso en línea:https://doaj.org/article/549518eff0424574b235a3ffcdcd80b9
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spelling oai:doaj.org-article:549518eff0424574b235a3ffcdcd80b92021-12-02T16:44:33ZOptimal management of coronary artery disease in cancer patients2095-882X10.1016/j.cdtm.2019.12.007https://doaj.org/article/549518eff0424574b235a3ffcdcd80b92019-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X19300933https://doaj.org/toc/2095-882XOwing to early diagnosis and rapid development of treatments for cancers, the five-year survival rate of all cancer types has markedly improved worldwide. Over time, however, there has been an increase in the number of cancer patients who develop coronary artery disease (CAD) due to different causes. First, many risk factors are shared between cancer and CAD. Second, inflammation and oxidative stress are common underlying pathogeneses in both disorders. Lastly, cancer therapy can result in endothelial injury, coronary artery spasm, and coagulation, thereby increasing the risk of CAD. As more cancer patients are being diagnosed with CAD, specialized cardiac care should be established to minimize the cardiovascular mortality of cancer survivors. Keywords: Cancer, Coronary artery disease, Cardio-oncologyXue-Jie HanJian-Qiang LiZulfiia KhannanovaYue LiKeAi Communications Co., Ltd.articleMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 5, Iss 4, Pp 221-233 (2019)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Xue-Jie Han
Jian-Qiang Li
Zulfiia Khannanova
Yue Li
Optimal management of coronary artery disease in cancer patients
description Owing to early diagnosis and rapid development of treatments for cancers, the five-year survival rate of all cancer types has markedly improved worldwide. Over time, however, there has been an increase in the number of cancer patients who develop coronary artery disease (CAD) due to different causes. First, many risk factors are shared between cancer and CAD. Second, inflammation and oxidative stress are common underlying pathogeneses in both disorders. Lastly, cancer therapy can result in endothelial injury, coronary artery spasm, and coagulation, thereby increasing the risk of CAD. As more cancer patients are being diagnosed with CAD, specialized cardiac care should be established to minimize the cardiovascular mortality of cancer survivors. Keywords: Cancer, Coronary artery disease, Cardio-oncology
format article
author Xue-Jie Han
Jian-Qiang Li
Zulfiia Khannanova
Yue Li
author_facet Xue-Jie Han
Jian-Qiang Li
Zulfiia Khannanova
Yue Li
author_sort Xue-Jie Han
title Optimal management of coronary artery disease in cancer patients
title_short Optimal management of coronary artery disease in cancer patients
title_full Optimal management of coronary artery disease in cancer patients
title_fullStr Optimal management of coronary artery disease in cancer patients
title_full_unstemmed Optimal management of coronary artery disease in cancer patients
title_sort optimal management of coronary artery disease in cancer patients
publisher KeAi Communications Co., Ltd.
publishDate 2019
url https://doaj.org/article/549518eff0424574b235a3ffcdcd80b9
work_keys_str_mv AT xuejiehan optimalmanagementofcoronaryarterydiseaseincancerpatients
AT jianqiangli optimalmanagementofcoronaryarterydiseaseincancerpatients
AT zulfiiakhannanova optimalmanagementofcoronaryarterydiseaseincancerpatients
AT yueli optimalmanagementofcoronaryarterydiseaseincancerpatients
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