Characteristics of cholera strains isolated in Kazakhstan

In the Republic of Kazakhstan there are three types of areas with different cholera infection risk levels for people. Within cholera epidemiological surveillance the cholera strains are annually isolated from people and the environment. In this research, we studied the cholera strains isolated in Ka...

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Autores principales:	I. B. Utepova, Z. A. Sagiyev, S. D. Alybayev, M. M. Kulbayeva, A. O. Ismailova, A. A. Abdirassilova, A. S. Zhunussova, A. A. Aldibekova, N. T. Karymsakova, A. M. Ismakova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	cholera microbiology genes antibacterial preparations strains Science Q
Acceso en línea:	https://doaj.org/article/54a8c0bfb0c546bd8448c1a21aa62036
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spelling	oai:doaj.org-article:54a8c0bfb0c546bd8448c1a21aa620362021-11-23T06:14:38ZCharacteristics of cholera strains isolated in Kazakhstan2541-94202587-959610.12737/article_59e8597494f893.97278235https://doaj.org/article/54a8c0bfb0c546bd8448c1a21aa620362017-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/440https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596In the Republic of Kazakhstan there are three types of areas with different cholera infection risk levels for people. Within cholera epidemiological surveillance the cholera strains are annually isolated from people and the environment. In this research, we studied the cholera strains isolated in Kazakhstan for 2013-2015 and they were selected for this study. All cholera strains were locally isolatedfrom people and the environment except one toxigenic imported strain of V. cholerae 01 lnaba which had genes of ctxAB, tcpA. The study showed that there were V cholerae strains which were atypical by their agglutination abilities and sensitivity to cholera phages. It can complicate the cholera laboratory diagnostics especially the diagnostics of V. cholerae О1 and for timely recognition of cholera it is necessary to carry out the diagnostics combined with molecular and genetic methods. For the study of antibiotic sensitivity or resistance we use eight antibacterial preparations. Cholera strains isolated in Kazakhstan did not have antibiotic resistance to the studied preparations. But the cholera strain brought from Pakistan was resistant to ciprofloxacin. The lack of strong resistance of local strains to the antibacterial drugs studied is encouraging in terms of conducting aetiotropic therapy. However, the possibility of entering of antibiotic-resistant strains into Kazakhstan obliges regularly to monitor strains for their sensitivity to antibacterial drugs.I. B. UtepovaZ. A. SagiyevS. D. AlybayevM. M. KulbayevaA. O. IsmailovaA. A. AbdirassilovaA. S. ZhunussovaA. A. AldibekovaN. T. KarymsakovaA. M. IsmakovaScientific Сentre for Family Health and Human Reproduction Problemsarticlecholeramicrobiologygenesantibacterial preparationsstrainsScienceQRUActa Biomedica Scientifica, Vol 2, Iss 5(1), Pp 100-105 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	cholera microbiology genes antibacterial preparations strains Science Q
spellingShingle	cholera microbiology genes antibacterial preparations strains Science Q I. B. Utepova Z. A. Sagiyev S. D. Alybayev M. M. Kulbayeva A. O. Ismailova A. A. Abdirassilova A. S. Zhunussova A. A. Aldibekova N. T. Karymsakova A. M. Ismakova Characteristics of cholera strains isolated in Kazakhstan
description	In the Republic of Kazakhstan there are three types of areas with different cholera infection risk levels for people. Within cholera epidemiological surveillance the cholera strains are annually isolated from people and the environment. In this research, we studied the cholera strains isolated in Kazakhstan for 2013-2015 and they were selected for this study. All cholera strains were locally isolatedfrom people and the environment except one toxigenic imported strain of V. cholerae 01 lnaba which had genes of ctxAB, tcpA. The study showed that there were V cholerae strains which were atypical by their agglutination abilities and sensitivity to cholera phages. It can complicate the cholera laboratory diagnostics especially the diagnostics of V. cholerae О1 and for timely recognition of cholera it is necessary to carry out the diagnostics combined with molecular and genetic methods. For the study of antibiotic sensitivity or resistance we use eight antibacterial preparations. Cholera strains isolated in Kazakhstan did not have antibiotic resistance to the studied preparations. But the cholera strain brought from Pakistan was resistant to ciprofloxacin. The lack of strong resistance of local strains to the antibacterial drugs studied is encouraging in terms of conducting aetiotropic therapy. However, the possibility of entering of antibiotic-resistant strains into Kazakhstan obliges regularly to monitor strains for their sensitivity to antibacterial drugs.
format	article
author	I. B. Utepova Z. A. Sagiyev S. D. Alybayev M. M. Kulbayeva A. O. Ismailova A. A. Abdirassilova A. S. Zhunussova A. A. Aldibekova N. T. Karymsakova A. M. Ismakova
author_facet	I. B. Utepova Z. A. Sagiyev S. D. Alybayev M. M. Kulbayeva A. O. Ismailova A. A. Abdirassilova A. S. Zhunussova A. A. Aldibekova N. T. Karymsakova A. M. Ismakova
author_sort	I. B. Utepova
title	Characteristics of cholera strains isolated in Kazakhstan
title_short	Characteristics of cholera strains isolated in Kazakhstan
title_full	Characteristics of cholera strains isolated in Kazakhstan
title_fullStr	Characteristics of cholera strains isolated in Kazakhstan
title_full_unstemmed	Characteristics of cholera strains isolated in Kazakhstan
title_sort	characteristics of cholera strains isolated in kazakhstan
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/54a8c0bfb0c546bd8448c1a21aa62036
work_keys_str_mv	AT ibutepova characteristicsofcholerastrainsisolatedinkazakhstan AT zasagiyev characteristicsofcholerastrainsisolatedinkazakhstan AT sdalybayev characteristicsofcholerastrainsisolatedinkazakhstan AT mmkulbayeva characteristicsofcholerastrainsisolatedinkazakhstan AT aoismailova characteristicsofcholerastrainsisolatedinkazakhstan AT aaabdirassilova characteristicsofcholerastrainsisolatedinkazakhstan AT aszhunussova characteristicsofcholerastrainsisolatedinkazakhstan AT aaaldibekova characteristicsofcholerastrainsisolatedinkazakhstan AT ntkarymsakova characteristicsofcholerastrainsisolatedinkazakhstan AT amismakova characteristicsofcholerastrainsisolatedinkazakhstan
_version_	1718417006220279808

Characteristics of cholera strains isolated in Kazakhstan

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