Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)

Awoke Seyoum Tegegne Department of Statistics, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Awoke Seyoum TegegneDepartment of Statistics, Bahir Dar University, Bahir Dar, EthiopiaTel +251918779451Email bisrategebrail@yahoo.comBackground: One of the chronic diseases, all over the world, d...

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Autor principal:	Tegegne AS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	joint modeling longitudinal data analysis hypertensive systolic diastolic type2 diabetes mixed model Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/54b189f08f194db3b6f7fa545b0692fb
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spelling	oai:doaj.org-article:54b189f08f194db3b6f7fa545b0692fb2021-12-02T15:50:41ZJoint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)1178-7007https://doaj.org/article/54b189f08f194db3b6f7fa545b0692fb2021-06-01T00:00:00Zhttps://www.dovepress.com/joint-predictors-of-hypertension-and-type-2-diabetes-among-adults-unde-peer-reviewed-fulltext-article-DMSOhttps://doaj.org/toc/1178-7007Awoke Seyoum Tegegne Department of Statistics, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Awoke Seyoum TegegneDepartment of Statistics, Bahir Dar University, Bahir Dar, EthiopiaTel +251918779451Email bisrategebrail@yahoo.comBackground: One of the chronic diseases, all over the world, due to its significant contribution to the existence of other health problems is hypertension. It is known that hypertensive patients exposed to diabetes and the reverse is also true. The objective of the current investigation was to identify joint risk factors for hypertension and type 2 diabetes for adults under treatment.Methods: A random sample of 748 hypertensive and type 2 diabetic patients was selected. A retrospective longitudinal study was conducted with the selected patients who were receiving treatment for both hypertension and type 2 diabetes. A joint linear mixed-effect model was used for data analysis in this investigation.Results: The current investigation revealed that age (β = 0.18, p-value = 0.04 for hypertension, β = 0.81, p-value = 0.02 for type 2 diabetes) and weight of patients (β = 0.52, p-value < 0.01 for hypertension, β = 0.32, p-value < 0.01 for type 2 diabetes) were positively and significantly associated with existence of hypertension and type 2 diabetes whereas visiting times (β = − 0.08, p-value = 0.04 for hypertension, β = − 0.38, p-value = 0.03 for type 2 diabetes) were negatively associated with the variables of interest. Similarly, patients who do not exercise, who smoke, and drink and patients with a family history of disease were positively associated with the existence of the variables of interest.Conclusion: Hypertension and diabetes are highly correlated and one is the causes of the other. Hypertensive and diabetic patients should be aware that they should stop drinking alcohol and smoking and should attend properly to their medication as prescribed by health staff. They should also be advised to undertake physical exercise to reduce risks related to these two correlated diseases.Keywords: joint modeling, longitudinal data analysis, hypertension, systolic, diastolic, type 2 diabetes, mixed modelTegegne ASDove Medical Pressarticlejoint modelinglongitudinal data analysishypertensivesystolicdiastolictype2 diabetesmixed modelSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 2453-2463 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	joint modeling longitudinal data analysis hypertensive systolic diastolic type2 diabetes mixed model Specialties of internal medicine RC581-951
spellingShingle	joint modeling longitudinal data analysis hypertensive systolic diastolic type2 diabetes mixed model Specialties of internal medicine RC581-951 Tegegne AS Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)
description	Awoke Seyoum Tegegne Department of Statistics, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Awoke Seyoum TegegneDepartment of Statistics, Bahir Dar University, Bahir Dar, EthiopiaTel +251918779451Email bisrategebrail@yahoo.comBackground: One of the chronic diseases, all over the world, due to its significant contribution to the existence of other health problems is hypertension. It is known that hypertensive patients exposed to diabetes and the reverse is also true. The objective of the current investigation was to identify joint risk factors for hypertension and type 2 diabetes for adults under treatment.Methods: A random sample of 748 hypertensive and type 2 diabetic patients was selected. A retrospective longitudinal study was conducted with the selected patients who were receiving treatment for both hypertension and type 2 diabetes. A joint linear mixed-effect model was used for data analysis in this investigation.Results: The current investigation revealed that age (β = 0.18, p-value = 0.04 for hypertension, β = 0.81, p-value = 0.02 for type 2 diabetes) and weight of patients (β = 0.52, p-value < 0.01 for hypertension, β = 0.32, p-value < 0.01 for type 2 diabetes) were positively and significantly associated with existence of hypertension and type 2 diabetes whereas visiting times (β = − 0.08, p-value = 0.04 for hypertension, β = − 0.38, p-value = 0.03 for type 2 diabetes) were negatively associated with the variables of interest. Similarly, patients who do not exercise, who smoke, and drink and patients with a family history of disease were positively associated with the existence of the variables of interest.Conclusion: Hypertension and diabetes are highly correlated and one is the causes of the other. Hypertensive and diabetic patients should be aware that they should stop drinking alcohol and smoking and should attend properly to their medication as prescribed by health staff. They should also be advised to undertake physical exercise to reduce risks related to these two correlated diseases.Keywords: joint modeling, longitudinal data analysis, hypertension, systolic, diastolic, type 2 diabetes, mixed model
format	article
author	Tegegne AS
author_facet	Tegegne AS
author_sort	Tegegne AS
title	Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)
title_short	Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)
title_full	Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)
title_fullStr	Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)
title_full_unstemmed	Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)
title_sort	joint predictors of hypertension and type 2 diabetes among adults under treatment in amhara region (north-western ethiopia)
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/54b189f08f194db3b6f7fa545b0692fb
work_keys_str_mv	AT tegegneas jointpredictorsofhypertensionandtype2diabetesamongadultsundertreatmentinamhararegionnorthwesternethiopia
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Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)

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