A Personalized Neoantigen Vaccine in Combination with Platinum-Based Chemotherapy Induces a T-Cell Response Coinciding with a Complete Response in Endometrial Carcinoma

A Personalized Neoantigen Vaccine in Combination with Platinum-Based Chemotherapy Induces a T-Cell Response Coinciding with a Complete Response in Endometrial Carcinoma

Endometrial cancer (EC) is a common gynecological malignancy and the fourth most common malignancy in European and North American women. Amongst EC, the advanced serous, p53-mutated, and pMMR subtypes have the highest risk of relapse despite optimal standard of care therapy. At present, there is no...

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Bibliographic Details
Main Authors: Alexandre Harari, Apostolos Sarivalasis, Kaat de Jonge, Anne-Christine Thierry, Florian Huber, Caroline Boudousquie, Laetitia Rossier, Angela Orcurto, Martina Imbimbo, Petra Baumgaertner, Michal Bassani-Sternberg, Lana E. Kandalaft
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
endometrial cancer
cancer vaccines
immunotherapy
neoantigens
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/54bbe941a68b4cdeb4848cf98f87ab84
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https://doaj.org/article/54bbe941a68b4cdeb4848cf98f87ab84

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