Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

The low throughput or content of current methods for the analysis of glycans-glycan binding proteins (GBPs) interactions hampers their clinical applications. Here, the authors conjugate synthesized glycans to Luminex beads to detect GBPs and apply it for the discovery of ovarian cancer biomarkers.

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Sharad Purohit, Tiehai Li, Wanyi Guan, Xuezheng Song, Jing Song, Yanna Tian, Lei Li, Ashok Sharma, Boying Dun, David Mysona, Sharad Ghamande, Bunja Rungruang, Richard D. Cummings, Peng George Wang, Jin-Xiong She
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/54bd91a6bdc84bbaaee3bb8a242ecc34
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:54bd91a6bdc84bbaaee3bb8a242ecc34
record_format	dspace
spelling	oai:doaj.org-article:54bd91a6bdc84bbaaee3bb8a242ecc342021-12-02T16:49:56ZMultiplex glycan bead array for high throughput and high content analyses of glycan binding proteins10.1038/s41467-017-02747-y2041-1723https://doaj.org/article/54bd91a6bdc84bbaaee3bb8a242ecc342018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02747-yhttps://doaj.org/toc/2041-1723The low throughput or content of current methods for the analysis of glycans-glycan binding proteins (GBPs) interactions hampers their clinical applications. Here, the authors conjugate synthesized glycans to Luminex beads to detect GBPs and apply it for the discovery of ovarian cancer biomarkers.Sharad PurohitTiehai LiWanyi GuanXuezheng SongJing SongYanna TianLei LiAshok SharmaBoying DunDavid MysonaSharad GhamandeBunja RungruangRichard D. CummingsPeng George WangJin-Xiong SheNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sharad Purohit Tiehai Li Wanyi Guan Xuezheng Song Jing Song Yanna Tian Lei Li Ashok Sharma Boying Dun David Mysona Sharad Ghamande Bunja Rungruang Richard D. Cummings Peng George Wang Jin-Xiong She Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
description	The low throughput or content of current methods for the analysis of glycans-glycan binding proteins (GBPs) interactions hampers their clinical applications. Here, the authors conjugate synthesized glycans to Luminex beads to detect GBPs and apply it for the discovery of ovarian cancer biomarkers.
format	article
author	Sharad Purohit Tiehai Li Wanyi Guan Xuezheng Song Jing Song Yanna Tian Lei Li Ashok Sharma Boying Dun David Mysona Sharad Ghamande Bunja Rungruang Richard D. Cummings Peng George Wang Jin-Xiong She
author_facet	Sharad Purohit Tiehai Li Wanyi Guan Xuezheng Song Jing Song Yanna Tian Lei Li Ashok Sharma Boying Dun David Mysona Sharad Ghamande Bunja Rungruang Richard D. Cummings Peng George Wang Jin-Xiong She
author_sort	Sharad Purohit
title	Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
title_short	Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
title_full	Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
title_fullStr	Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
title_full_unstemmed	Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
title_sort	multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/54bd91a6bdc84bbaaee3bb8a242ecc34
work_keys_str_mv	AT sharadpurohit multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT tiehaili multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT wanyiguan multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT xuezhengsong multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT jingsong multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT yannatian multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT leili multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT ashoksharma multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT boyingdun multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT davidmysona multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT sharadghamande multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT bunjarungruang multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT richarddcummings multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT penggeorgewang multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins AT jinxiongshe multiplexglycanbeadarrayforhighthroughputandhighcontentanalysesofglycanbindingproteins
_version_	1718383158600138752

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Documents similaires