Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

AtEH/Pan1 proteins contain two N-terminal Eps15 homology (EH) domains and are subunits of the endocytic TPLATE complex present in plants. Here, the authors combine X-ray crystallography, NMR and MD simulations with biochemical and in planta analysis to characterize the two AtEH1/Pan1 EH domains and...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Klaas Yperman, Anna C. Papageorgiou, Romain Merceron, Steven De Munck, Yehudi Bloch, Dominique Eeckhout, Qihang Jiang, Pieter Tack, Rosa Grigoryan, Thomas Evangelidis, Jelle Van Leene, Laszlo Vincze, Peter Vandenabeele, Frank Vanhaecke, Martin Potocký, Geert De Jaeger, Savvas N. Savvides, Konstantinos Tripsianes, Roman Pleskot, Daniel Van Damme
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/54c36870e5d64914ba2d301548b4af42
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:54c36870e5d64914ba2d301548b4af42
record_format	dspace
spelling	oai:doaj.org-article:54c36870e5d64914ba2d301548b4af422021-12-02T14:49:22ZDistinct EH domains of the endocytic TPLATE complex confer lipid and protein binding10.1038/s41467-021-23314-62041-1723https://doaj.org/article/54c36870e5d64914ba2d301548b4af422021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23314-6https://doaj.org/toc/2041-1723AtEH/Pan1 proteins contain two N-terminal Eps15 homology (EH) domains and are subunits of the endocytic TPLATE complex present in plants. Here, the authors combine X-ray crystallography, NMR and MD simulations with biochemical and in planta analysis to characterize the two AtEH1/Pan1 EH domains and reveal their structural differences and complementary functional roles.Klaas YpermanAnna C. PapageorgiouRomain MerceronSteven De MunckYehudi BlochDominique EeckhoutQihang JiangPieter TackRosa GrigoryanThomas EvangelidisJelle Van LeeneLaszlo VinczePeter VandenabeeleFrank VanhaeckeMartin PotockýGeert De JaegerSavvas N. SavvidesKonstantinos TripsianesRoman PleskotDaniel Van DammeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Klaas Yperman Anna C. Papageorgiou Romain Merceron Steven De Munck Yehudi Bloch Dominique Eeckhout Qihang Jiang Pieter Tack Rosa Grigoryan Thomas Evangelidis Jelle Van Leene Laszlo Vincze Peter Vandenabeele Frank Vanhaecke Martin Potocký Geert De Jaeger Savvas N. Savvides Konstantinos Tripsianes Roman Pleskot Daniel Van Damme Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
description	AtEH/Pan1 proteins contain two N-terminal Eps15 homology (EH) domains and are subunits of the endocytic TPLATE complex present in plants. Here, the authors combine X-ray crystallography, NMR and MD simulations with biochemical and in planta analysis to characterize the two AtEH1/Pan1 EH domains and reveal their structural differences and complementary functional roles.
format	article
author	Klaas Yperman Anna C. Papageorgiou Romain Merceron Steven De Munck Yehudi Bloch Dominique Eeckhout Qihang Jiang Pieter Tack Rosa Grigoryan Thomas Evangelidis Jelle Van Leene Laszlo Vincze Peter Vandenabeele Frank Vanhaecke Martin Potocký Geert De Jaeger Savvas N. Savvides Konstantinos Tripsianes Roman Pleskot Daniel Van Damme
author_facet	Klaas Yperman Anna C. Papageorgiou Romain Merceron Steven De Munck Yehudi Bloch Dominique Eeckhout Qihang Jiang Pieter Tack Rosa Grigoryan Thomas Evangelidis Jelle Van Leene Laszlo Vincze Peter Vandenabeele Frank Vanhaecke Martin Potocký Geert De Jaeger Savvas N. Savvides Konstantinos Tripsianes Roman Pleskot Daniel Van Damme
author_sort	Klaas Yperman
title	Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
title_short	Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
title_full	Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
title_fullStr	Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
title_full_unstemmed	Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
title_sort	distinct eh domains of the endocytic tplate complex confer lipid and protein binding
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/54c36870e5d64914ba2d301548b4af42
work_keys_str_mv	AT klaasyperman distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT annacpapageorgiou distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT romainmerceron distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT stevendemunck distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT yehudibloch distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT dominiqueeeckhout distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT qihangjiang distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT pietertack distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT rosagrigoryan distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT thomasevangelidis distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT jellevanleene distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT laszlovincze distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT petervandenabeele distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT frankvanhaecke distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT martinpotocky distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT geertdejaeger distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT savvasnsavvides distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT konstantinostripsianes distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT romanpleskot distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding AT danielvandamme distinctehdomainsoftheendocytictplatecomplexconferlipidandproteinbinding
_version_	1718389508657905664

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Ejemplares similares