Global microRNA profiling of the mouse ventricles during development of severe hypertrophic cardiomyopathy and heart failure.

MicroRNAs (miRNAs) regulate post-transcriptional gene expression during development and disease. We have determined the miRNA expression levels of early- and end-stage hypertrophic cardiomyopathy (HCM) in a severe, transgenic mouse model of the disease. Five miRNAs were differentially expressed at a...

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Autores principales: Richard D Bagnall, Tatiana Tsoutsman, Rhian E Shephard, William Ritchie, Christopher Semsarian
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/54c9e277339248f1b3d06f906e6953ef
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