Immune system cells from COVID-19 patients display compromised mitochondrial-nuclear expression co-regulation and rewiring toward glycolysis
Summary: Mitochondria are pivotal for bioenergetics, as well as in cellular response to viral infections. Nevertheless, their role in COVID-19 was largely overlooked. Here, we analyzed available bulk RNA-seq datasets from COVID-19 patients and corresponding healthy controls (three blood datasets, N ...
Guardado en:
Autores principales: | Hadar Medini, Amit Zirman, Dan Mishmar |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/54cb9f499310415dae8304ed758a5b28 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Intranasal vaccination with a Newcastle disease virus-vectored vaccine protects hamsters from SARS-CoV-2 infection and disease
por: Bryce M. Warner, et al.
Publicado: (2021) -
Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineages
por: Caroline Gravel, et al.
Publicado: (2021) -
Prestimulation of CD2 confers resistance to HIV-1 latent infection in blood resting CD4 T cells
por: Sijia He, et al.
Publicado: (2021) -
IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cells
por: Tomas Raul Wiche Salinas, et al.
Publicado: (2021) -
Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium
por: Jacob Thyrsted, et al.
Publicado: (2021)