Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators

Recent experimental work has revealed non-linear dendritic integration in interneurons. Here, the authors show, through detailed biophysical modeling, that fast spiking interneurons are better described with a 2-stage artificial neural network model calling into question the use of point neuron mode...

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Autores principales: Alexandra Tzilivaki, George Kastellakis, Panayiota Poirazi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/54e1f0705b4347339b0c67285006dbd5
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Sumario:Recent experimental work has revealed non-linear dendritic integration in interneurons. Here, the authors show, through detailed biophysical modeling, that fast spiking interneurons are better described with a 2-stage artificial neural network model calling into question the use of point neuron models.