A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.

A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.

As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to MM. In this study, 363 SNPs in 65 gene regions belonging to the pigmentation pat...

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Autores principales: Maider Ibarrola-Villava, Lara P Fernandez, Santos Alonso, M Dolores Boyano, Maria Peña-Chilet, Guillermo Pita, Jose A Aviles, Matias Mayor, Cristina Gomez-Fernandez, Beatriz Casado, Manuel Martin-Gonzalez, Neskuts Izagirre, Concepcion De la Rua, Aintzane Asumendi, Gorka Perez-Yarza, Yoana Arroyo-Berdugo, Enrique Boldo, Rafael Lozoya, Arantxa Torrijos-Aguilar, Ana Pitarch, Gerard Pitarch, Jose M Sanchez-Motilla, Francisca Valcuende-Cavero, Gloria Tomas-Cabedo, Gemma Perez-Pastor, Jose L Diaz-Perez, Jesus Gardeazabal, Iñigo Martinez de Lizarduy, Ana Sanchez-Diez, Carlos Valdes, Angel Pizarro, Mariano Casado, Gregorio Carretero, Rafael Botella-Estrada, Eduardo Nagore, Pablo Lazaro, Ana Lluch, Javier Benitez, Conrado Martinez-Cadenas, Gloria Ribas
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/54eddd4350a44dff8928703af2a4810d
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