Role of Glutathione in Buffering Excess Intracellular Copper in <italic toggle="yes">Streptococcus pyogenes</italic>

Role of Glutathione in Buffering Excess Intracellular Copper in <italic toggle="yes">Streptococcus pyogenes</italic>

ABSTRACT Copper (Cu) is an essential metal for bacterial physiology but in excess it is bacteriotoxic. To limit Cu levels in the cytoplasm, most bacteria possess a transcriptionally responsive system for Cu export. In the Gram-positive human pathogen Streptococcus pyogenes (group A Streptococcus [GA...

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Bibliographic Details
Main Authors: Louisa J. Stewart, Cheryl-lynn Y. Ong, May M. Zhang, Stephan Brouwer, Liam McIntyre, Mark R. Davies, Mark J. Walker, Alastair G. McEwan, Kevin J. Waldron, Karrera Y. Djoko
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
copper homeostasis
copper export
metal buffer
glutathione
group A Streptococcus
copper stress
Microbiology
QR1-502
Online Access:https://doaj.org/article/54f175ae2c47421291edd930a86b688d
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https://doaj.org/article/54f175ae2c47421291edd930a86b688d

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