Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm

To evaluate choroidal volume and thickness changes after photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Chronic CSC eyes with a history of PDT were selected. Average choroidal volume, average choroidal thickness, the maximum and minimum choroidal thickness of the macu...

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Autores principales: Miki Sato-Akushichi, Shinji Ono, Gerd Klose, Youngseok Song
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:54f9b3b20ae24ac0be1ff32e7f66ff612021-11-25T18:39:39ZChoroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm10.3390/ph141111401424-8247https://doaj.org/article/54f9b3b20ae24ac0be1ff32e7f66ff612021-11-01T00:00:00Zhttps://www.mdpi.com/1424-8247/14/11/1140https://doaj.org/toc/1424-8247To evaluate choroidal volume and thickness changes after photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Chronic CSC eyes with a history of PDT were selected. Average choroidal volume, average choroidal thickness, the maximum and minimum choroidal thickness of the macula irradiated area and peripheral non-irradiated areas before and after one and three months of treatment were examined. A total of 14 patients with chronic CSC and 9 controls without any eye pathology were enrolled. The mean choroidal volume in CSC before and, and after one and three months of treatment were 2.36 (standard deviation: 0.70), 1.90 (0.69), 1.86 (0.66) mm<sup>3</sup> for the central area, 1.25 (0.38), 1.14 (0.35), 1.13 (0.34) mm<sup>3</sup> for superior nasal area, 1.47 (0.41), 1.28 (0.43), 1.26 (0.43) mm<sup>3</sup> for superior temporal area, 1.07 (0.49), 0.95 (0.38), 0.93 (0.35) mm<sup>3</sup> for inferior nasal area, 1.17 (0.38), 1.04 (0.32), 1.03 (0.33) mm<sup>3</sup> for inferior temporal area. This study revealed the choroidal volume changes in a short period after PDT and a decrease in unirradiated choroidal volume was also shown after the treatment. The algorithm provided on the ARI Network enables to evaluate the choroidal changes quantitatively and qualitatively.Miki Sato-AkushichiShinji OnoGerd KloseYoungseok SongMDPI AGarticlecentral serous chorioretinopathyphotodynamic therapychoroidal volumechoroidal thicknessnew algorithmMedicineRPharmacy and materia medicaRS1-441ENPharmaceuticals, Vol 14, Iss 1140, p 1140 (2021)
institution DOAJ
collection DOAJ
language EN
topic central serous chorioretinopathy
photodynamic therapy
choroidal volume
choroidal thickness
new algorithm
Medicine
R
Pharmacy and materia medica
RS1-441
spellingShingle central serous chorioretinopathy
photodynamic therapy
choroidal volume
choroidal thickness
new algorithm
Medicine
R
Pharmacy and materia medica
RS1-441
Miki Sato-Akushichi
Shinji Ono
Gerd Klose
Youngseok Song
Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm
description To evaluate choroidal volume and thickness changes after photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Chronic CSC eyes with a history of PDT were selected. Average choroidal volume, average choroidal thickness, the maximum and minimum choroidal thickness of the macula irradiated area and peripheral non-irradiated areas before and after one and three months of treatment were examined. A total of 14 patients with chronic CSC and 9 controls without any eye pathology were enrolled. The mean choroidal volume in CSC before and, and after one and three months of treatment were 2.36 (standard deviation: 0.70), 1.90 (0.69), 1.86 (0.66) mm<sup>3</sup> for the central area, 1.25 (0.38), 1.14 (0.35), 1.13 (0.34) mm<sup>3</sup> for superior nasal area, 1.47 (0.41), 1.28 (0.43), 1.26 (0.43) mm<sup>3</sup> for superior temporal area, 1.07 (0.49), 0.95 (0.38), 0.93 (0.35) mm<sup>3</sup> for inferior nasal area, 1.17 (0.38), 1.04 (0.32), 1.03 (0.33) mm<sup>3</sup> for inferior temporal area. This study revealed the choroidal volume changes in a short period after PDT and a decrease in unirradiated choroidal volume was also shown after the treatment. The algorithm provided on the ARI Network enables to evaluate the choroidal changes quantitatively and qualitatively.
format article
author Miki Sato-Akushichi
Shinji Ono
Gerd Klose
Youngseok Song
author_facet Miki Sato-Akushichi
Shinji Ono
Gerd Klose
Youngseok Song
author_sort Miki Sato-Akushichi
title Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm
title_short Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm
title_full Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm
title_fullStr Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm
title_full_unstemmed Choroidal Volume Evaluation after Photodynamic Therapy Using New Optical Coherence Tomography Imaging Algorithm
title_sort choroidal volume evaluation after photodynamic therapy using new optical coherence tomography imaging algorithm
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/54f9b3b20ae24ac0be1ff32e7f66ff61
work_keys_str_mv AT mikisatoakushichi choroidalvolumeevaluationafterphotodynamictherapyusingnewopticalcoherencetomographyimagingalgorithm
AT shinjiono choroidalvolumeevaluationafterphotodynamictherapyusingnewopticalcoherencetomographyimagingalgorithm
AT gerdklose choroidalvolumeevaluationafterphotodynamictherapyusingnewopticalcoherencetomographyimagingalgorithm
AT youngseoksong choroidalvolumeevaluationafterphotodynamictherapyusingnewopticalcoherencetomographyimagingalgorithm
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