Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best...

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Autores principales:	Anna Rosińska-Więckowicz, Magdalena Jałowska, Monika Bowszyc-Dmochowska, Marian Dmochowski
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	bullous pemphigoid infants autoimmune blistering COVID-19 RT-PCR Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/550b6587ad1743099d3911f716ddc3a7
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spelling	oai:doaj.org-article:550b6587ad1743099d3911f716ddc3a72021-11-22T05:30:30ZCase Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative2296-858X10.3389/fmed.2021.760823https://doaj.org/article/550b6587ad1743099d3911f716ddc3a72021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.760823/fullhttps://doaj.org/toc/2296-858XBullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.Anna Rosińska-WięckowiczMagdalena JałowskaMonika Bowszyc-DmochowskaMarian DmochowskiFrontiers Media S.A.articlebullous pemphigoidinfantsautoimmune blisteringCOVID-19RT-PCRMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bullous pemphigoid infants autoimmune blistering COVID-19 RT-PCR Medicine (General) R5-920
spellingShingle	bullous pemphigoid infants autoimmune blistering COVID-19 RT-PCR Medicine (General) R5-920 Anna Rosińska-Więckowicz Magdalena Jałowska Monika Bowszyc-Dmochowska Marian Dmochowski Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
description	Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.
format	article
author	Anna Rosińska-Więckowicz Magdalena Jałowska Monika Bowszyc-Dmochowska Marian Dmochowski
author_facet	Anna Rosińska-Więckowicz Magdalena Jałowska Monika Bowszyc-Dmochowska Marian Dmochowski
author_sort	Anna Rosińska-Więckowicz
title	Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_short	Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_full	Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_fullStr	Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_full_unstemmed	Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_sort	case report: infantile bullous pemphigoid: triggering by covid-19 is speculative
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/550b6587ad1743099d3911f716ddc3a7
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Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

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