Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease

Temesgen Mulugeta, Kabaye Kumela, Legese Chelkeba Department of Clinical Pharmacy, Institute of Health, Jimma University, Jimma, Oromia, EthiopiaCorrespondence: Temesgen MulugetaDepartment of Clinical Pharmacy, Institute of Health, Jimma University, P. O Box: 378, Jimma, Oromia, EthiopiaTel +251 917...

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Autores principales:	Mulugeta T, Kumela K, Chelkeba L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	rheumatic heart disease clinical characteristics echocardiography management Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/55141dc24d93418998940c92d8cee80f
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spelling	oai:doaj.org-article:55141dc24d93418998940c92d8cee80f2021-12-02T13:16:05ZClinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease1179-156Xhttps://doaj.org/article/55141dc24d93418998940c92d8cee80f2020-10-01T00:00:00Zhttps://www.dovepress.com/clinical-echocardiographic-characteristics-and-management-practices-in-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XTemesgen Mulugeta, Kabaye Kumela, Legese Chelkeba Department of Clinical Pharmacy, Institute of Health, Jimma University, Jimma, Oromia, EthiopiaCorrespondence: Temesgen MulugetaDepartment of Clinical Pharmacy, Institute of Health, Jimma University, P. O Box: 378, Jimma, Oromia, EthiopiaTel +251 917734764Email temesgen.mulugeta@ju.edu.etBackground: Rheumatic heart disease (RHD) is the long-term consequence of acute rheumatic fever (ARF), continues unabated among middle-income and low-income countries. Thus, this study aimed to assess clinical characteristics, echocardiographic characteristics, and management practice of RHD patients.Methods: Hospital-based prospective cross-sectional study was used. The data were collected from medical records of consecutive patients admitted to medical wards during the study period. The data were cleaned and analyzed using SPSS version 20. Descriptive statistics were used to describe the data. Chi-square was used to compare proportions between categorical variables.Results: Forty-seven patients with a median (IQR) age of 28.0 (17.0-40.0) years were included. Pan systolic murmur was reported in 91.50% of patients. Forty-two (89.4%) of patients were presented with congestive heart failure and 23 (48.9%) with atrial fibrillation. Mitral valve leaflet thickening and calcification with restriction of motion were reported in 91.5% of patients. Mitral regurgitation (MR) (87.2%) and stenosis (MS) (85.1%) were the most common valvular lesions. The combinations of three (MR+MS+TR) 14 (29.8%) and four (MR+MS+TR+AR) 13 (27.7%) valve diseases were most commonly reported. Diuretics (95.7%), anticoagulants (38.3%), digoxin (36.2%), and beta-blockers (34.0%) were among the commonly prescribed medications.Conclusion: Rheumatic heart disease affected younger adults. Pansystolic murmur was reported in nearly all patients. Congestive heart failure and atrial fibrillation were common clinical presentations. Morphologic changes in mitral valve and pathologic mitral regurgitation were the most common echocardiographic reports. Cardiovascular medications were commonly utilized for symptomatic management of complications Therefore, echocardiography should be done routinely for patients with RHD, focusing on younger adults, to facilitate diagnosis and treatment before complications develop.Keywords: rheumatic heart disease, clinical characteristics, echocardiography, managementMulugeta TKumela KChelkeba LDove Medical Pressarticlerheumatic heart diseaseclinical characteristicsechocardiographymanagementDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 12, Pp 233-239 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	rheumatic heart disease clinical characteristics echocardiography management Diseases of the musculoskeletal system RC925-935
spellingShingle	rheumatic heart disease clinical characteristics echocardiography management Diseases of the musculoskeletal system RC925-935 Mulugeta T Kumela K Chelkeba L Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease
description	Temesgen Mulugeta, Kabaye Kumela, Legese Chelkeba Department of Clinical Pharmacy, Institute of Health, Jimma University, Jimma, Oromia, EthiopiaCorrespondence: Temesgen MulugetaDepartment of Clinical Pharmacy, Institute of Health, Jimma University, P. O Box: 378, Jimma, Oromia, EthiopiaTel +251 917734764Email temesgen.mulugeta@ju.edu.etBackground: Rheumatic heart disease (RHD) is the long-term consequence of acute rheumatic fever (ARF), continues unabated among middle-income and low-income countries. Thus, this study aimed to assess clinical characteristics, echocardiographic characteristics, and management practice of RHD patients.Methods: Hospital-based prospective cross-sectional study was used. The data were collected from medical records of consecutive patients admitted to medical wards during the study period. The data were cleaned and analyzed using SPSS version 20. Descriptive statistics were used to describe the data. Chi-square was used to compare proportions between categorical variables.Results: Forty-seven patients with a median (IQR) age of 28.0 (17.0-40.0) years were included. Pan systolic murmur was reported in 91.50% of patients. Forty-two (89.4%) of patients were presented with congestive heart failure and 23 (48.9%) with atrial fibrillation. Mitral valve leaflet thickening and calcification with restriction of motion were reported in 91.5% of patients. Mitral regurgitation (MR) (87.2%) and stenosis (MS) (85.1%) were the most common valvular lesions. The combinations of three (MR+MS+TR) 14 (29.8%) and four (MR+MS+TR+AR) 13 (27.7%) valve diseases were most commonly reported. Diuretics (95.7%), anticoagulants (38.3%), digoxin (36.2%), and beta-blockers (34.0%) were among the commonly prescribed medications.Conclusion: Rheumatic heart disease affected younger adults. Pansystolic murmur was reported in nearly all patients. Congestive heart failure and atrial fibrillation were common clinical presentations. Morphologic changes in mitral valve and pathologic mitral regurgitation were the most common echocardiographic reports. Cardiovascular medications were commonly utilized for symptomatic management of complications Therefore, echocardiography should be done routinely for patients with RHD, focusing on younger adults, to facilitate diagnosis and treatment before complications develop.Keywords: rheumatic heart disease, clinical characteristics, echocardiography, management
format	article
author	Mulugeta T Kumela K Chelkeba L
author_facet	Mulugeta T Kumela K Chelkeba L
author_sort	Mulugeta T
title	Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease
title_short	Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease
title_full	Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease
title_fullStr	Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease
title_full_unstemmed	Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease
title_sort	clinical, echocardiographic characteristics and management practices in patients with rheumatic valvular heart disease
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/55141dc24d93418998940c92d8cee80f
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Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease

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