$Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel$
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Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel

The cardiac autonomic nervous system produces various neuropeptides, such as neurokinin substance-P (Sub-P), whose function remains largely unclear. Here, authors show that Sub-P causes a receptor-mediated prolongation of the atrial action potential through a reduced background potassium current, an...

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Autores principales:	Marieke W. Veldkamp, Guillaume S. C. Geuzebroek, Antonius Baartscheer, Arie O. Verkerk, Cees A. Schumacher, Gedeon G. Suarez, Wouter R. Berger, Simona Casini, Shirley C. M. van Amersfoorth, Koen T. Scholman, Antoine H. G. Driessen, Charly N. W. Belterman, Antoni C. G. van Ginneken, Joris R. de Groot, Jacques M. T. de Bakker, Carol Ann Remme, Bas J. Boukens, Ruben Coronel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/551537e643be4d3280a69b3581a50647
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Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel

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