Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues

Biofilm formation and antibiotic tolerance are regulated in Pseudomonas aeruginosa by the protein PA1396, which responds to diffusible signal factors (DSFs) produced by other bacteria. Here, An et al. synthesize DSF analogues that modulate PA1396 activity and thus biofilm formation and antibiotic to...

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Autores principales:	Shi-qi An, Julie Murtagh, Kate B. Twomey, Manoj K. Gupta, Timothy P. O’Sullivan, Rebecca Ingram, Miguel A. Valvano, Ji-liang Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/551913c042084dbbbcb6ec863181c625
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spelling	oai:doaj.org-article:551913c042084dbbbcb6ec863181c6252021-12-02T14:35:31ZModulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues10.1038/s41467-019-10271-42041-1723https://doaj.org/article/551913c042084dbbbcb6ec863181c6252019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10271-4https://doaj.org/toc/2041-1723Biofilm formation and antibiotic tolerance are regulated in Pseudomonas aeruginosa by the protein PA1396, which responds to diffusible signal factors (DSFs) produced by other bacteria. Here, An et al. synthesize DSF analogues that modulate PA1396 activity and thus biofilm formation and antibiotic tolerance.Shi-qi AnJulie MurtaghKate B. TwomeyManoj K. GuptaTimothy P. O’SullivanRebecca IngramMiguel A. ValvanoJi-liang TangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shi-qi An Julie Murtagh Kate B. Twomey Manoj K. Gupta Timothy P. O’Sullivan Rebecca Ingram Miguel A. Valvano Ji-liang Tang Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues
description	Biofilm formation and antibiotic tolerance are regulated in Pseudomonas aeruginosa by the protein PA1396, which responds to diffusible signal factors (DSFs) produced by other bacteria. Here, An et al. synthesize DSF analogues that modulate PA1396 activity and thus biofilm formation and antibiotic tolerance.
format	article
author	Shi-qi An Julie Murtagh Kate B. Twomey Manoj K. Gupta Timothy P. O’Sullivan Rebecca Ingram Miguel A. Valvano Ji-liang Tang
author_facet	Shi-qi An Julie Murtagh Kate B. Twomey Manoj K. Gupta Timothy P. O’Sullivan Rebecca Ingram Miguel A. Valvano Ji-liang Tang
author_sort	Shi-qi An
title	Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues
title_short	Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues
title_full	Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues
title_fullStr	Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues
title_full_unstemmed	Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues
title_sort	modulation of antibiotic sensitivity and biofilm formation in pseudomonas aeruginosa by interspecies signal analogues
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/551913c042084dbbbcb6ec863181c625
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Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues

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