Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine

This review is dedicated to a comprehensive description of the latest achievements in the chemical functionalization routes and applications of carbon nanomaterials (CNMs), such as carbon nanotubes, graphene, and graphene nanoribbons. The review starts from the description of noncovalent and covalen...

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Autores principales: Maria G. Burdanova, Marianna V. Kharlamova, Christian Kramberger, Maxim P. Nikitin
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:551bc9d46e97421da3591f88f2ec94462021-11-25T18:31:46ZApplications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine10.3390/nano111130202079-4991https://doaj.org/article/551bc9d46e97421da3591f88f2ec94462021-11-01T00:00:00Zhttps://www.mdpi.com/2079-4991/11/11/3020https://doaj.org/toc/2079-4991This review is dedicated to a comprehensive description of the latest achievements in the chemical functionalization routes and applications of carbon nanomaterials (CNMs), such as carbon nanotubes, graphene, and graphene nanoribbons. The review starts from the description of noncovalent and covalent exohedral modification approaches, as well as an endohedral functionalization method. After that, the methods to improve the functionalities of CNMs are highlighted. These methods include the functionalization for improving the hydrophilicity, biocompatibility, blood circulation time and tumor accumulation, and the cellular uptake and selectivity. The main part of this review includes the description of the applications of functionalized CNMs in bioimaging, drug delivery, and biosensors. Then, the toxicity studies of CNMs are highlighted. Finally, the further directions of the development of the field are presented.Maria G. BurdanovaMarianna V. KharlamovaChristian KrambergerMaxim P. NikitinMDPI AGarticlecarbon nanotubesgraphenegraphene nanoribbonsfunctionalizationbiosensingbioimagingChemistryQD1-999ENNanomaterials, Vol 11, Iss 3020, p 3020 (2021)
institution DOAJ
collection DOAJ
language EN
topic carbon nanotubes
graphene
graphene nanoribbons
functionalization
biosensing
bioimaging
Chemistry
QD1-999
spellingShingle carbon nanotubes
graphene
graphene nanoribbons
functionalization
biosensing
bioimaging
Chemistry
QD1-999
Maria G. Burdanova
Marianna V. Kharlamova
Christian Kramberger
Maxim P. Nikitin
Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine
description This review is dedicated to a comprehensive description of the latest achievements in the chemical functionalization routes and applications of carbon nanomaterials (CNMs), such as carbon nanotubes, graphene, and graphene nanoribbons. The review starts from the description of noncovalent and covalent exohedral modification approaches, as well as an endohedral functionalization method. After that, the methods to improve the functionalities of CNMs are highlighted. These methods include the functionalization for improving the hydrophilicity, biocompatibility, blood circulation time and tumor accumulation, and the cellular uptake and selectivity. The main part of this review includes the description of the applications of functionalized CNMs in bioimaging, drug delivery, and biosensors. Then, the toxicity studies of CNMs are highlighted. Finally, the further directions of the development of the field are presented.
format article
author Maria G. Burdanova
Marianna V. Kharlamova
Christian Kramberger
Maxim P. Nikitin
author_facet Maria G. Burdanova
Marianna V. Kharlamova
Christian Kramberger
Maxim P. Nikitin
author_sort Maria G. Burdanova
title Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine
title_short Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine
title_full Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine
title_fullStr Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine
title_full_unstemmed Applications of Pristine and Functionalized Carbon Nanotubes, Graphene, and Graphene Nanoribbons in Biomedicine
title_sort applications of pristine and functionalized carbon nanotubes, graphene, and graphene nanoribbons in biomedicine
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/551bc9d46e97421da3591f88f2ec9446
work_keys_str_mv AT mariagburdanova applicationsofpristineandfunctionalizedcarbonnanotubesgrapheneandgraphenenanoribbonsinbiomedicine
AT mariannavkharlamova applicationsofpristineandfunctionalizedcarbonnanotubesgrapheneandgraphenenanoribbonsinbiomedicine
AT christiankramberger applicationsofpristineandfunctionalizedcarbonnanotubesgrapheneandgraphenenanoribbonsinbiomedicine
AT maximpnikitin applicationsofpristineandfunctionalizedcarbonnanotubesgrapheneandgraphenenanoribbonsinbiomedicine
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