Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.

Hepatitis B is a leading cause of death worldwide. Here, we performed a large, population-based, cross-sectional study in Chongqing, China from 2011 to 2016 to assess the prevalence of HBsAg among couples of reproductive age, to predict subsequent trends, and to provide evidence for the WHO goal of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Qing Chen, Jun Liu, Yang He, Liu Yang, Huiqiang Luo, Yixi Wang, Xuewen Zhang, Ningxiu Li
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/551d0c918865420881829858172bc333
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:551d0c918865420881829858172bc333
record_format	dspace
spelling	oai:doaj.org-article:551d0c918865420881829858172bc3332021-12-02T20:13:04ZPrevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.1932-620310.1371/journal.pone.0260028https://doaj.org/article/551d0c918865420881829858172bc3332021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0260028https://doaj.org/toc/1932-6203Hepatitis B is a leading cause of death worldwide. Here, we performed a large, population-based, cross-sectional study in Chongqing, China from 2011 to 2016 to assess the prevalence of HBsAg among couples of reproductive age, to predict subsequent trends, and to provide evidence for the WHO goal of "the elimination of viral hepatitis as a public health threat by 2030". A total of 386,286 couples aged 20 to 49 years were enrolled in the study. Approximately 14.35% of couples were HBsAg positive, including 95.00% with discordant HBsAg positivity. HBsAg prevalence was higher in men than in women. Among different occupations, the two categories of "houseworker" (female 6.73%, male 9.99%) and "unemployed" (female 6.64%, male 9.94%) showed the highest HBsAg positivity. In different regions, the lowest prevalence appeared in southeastern Chongqing (female 4.87%, male 7.71%). In 2030, the HBsAg positivity rate is expected to be 2.79%, 7.27% and 5.13% in females, males, and the whole population, respectively. According to the trends, this rate would drop to less than 2% in 2034, 2078 and 2051. In conclusion, the HBsAg prevalence in Chongqing is still relatively high compared with that in other parts of western China, especially among reproductive-age men. HBsAg-positive couples should be taken as an important unit of care. Vaccination is necessary before pregnancy if no antibody is found. More attention should be given to people without stable jobs. HBsAg-positive rate will decrease perceptibly by 2030 and will reach the level of low in epidemic areas by 2050.Qing ChenJun LiuYang HeLiu YangHuiqiang LuoYixi WangXuewen ZhangNingxiu LiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0260028 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Qing Chen Jun Liu Yang He Liu Yang Huiqiang Luo Yixi Wang Xuewen Zhang Ningxiu Li Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.
description	Hepatitis B is a leading cause of death worldwide. Here, we performed a large, population-based, cross-sectional study in Chongqing, China from 2011 to 2016 to assess the prevalence of HBsAg among couples of reproductive age, to predict subsequent trends, and to provide evidence for the WHO goal of "the elimination of viral hepatitis as a public health threat by 2030". A total of 386,286 couples aged 20 to 49 years were enrolled in the study. Approximately 14.35% of couples were HBsAg positive, including 95.00% with discordant HBsAg positivity. HBsAg prevalence was higher in men than in women. Among different occupations, the two categories of "houseworker" (female 6.73%, male 9.99%) and "unemployed" (female 6.64%, male 9.94%) showed the highest HBsAg positivity. In different regions, the lowest prevalence appeared in southeastern Chongqing (female 4.87%, male 7.71%). In 2030, the HBsAg positivity rate is expected to be 2.79%, 7.27% and 5.13% in females, males, and the whole population, respectively. According to the trends, this rate would drop to less than 2% in 2034, 2078 and 2051. In conclusion, the HBsAg prevalence in Chongqing is still relatively high compared with that in other parts of western China, especially among reproductive-age men. HBsAg-positive couples should be taken as an important unit of care. Vaccination is necessary before pregnancy if no antibody is found. More attention should be given to people without stable jobs. HBsAg-positive rate will decrease perceptibly by 2030 and will reach the level of low in epidemic areas by 2050.
format	article
author	Qing Chen Jun Liu Yang He Liu Yang Huiqiang Luo Yixi Wang Xuewen Zhang Ningxiu Li
author_facet	Qing Chen Jun Liu Yang He Liu Yang Huiqiang Luo Yixi Wang Xuewen Zhang Ningxiu Li
author_sort	Qing Chen
title	Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.
title_short	Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.
title_full	Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.
title_fullStr	Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.
title_full_unstemmed	Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.
title_sort	prevalence of hbsag among reproductive age couples in chongqing: a population-based, cross-sectional study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/551d0c918865420881829858172bc333
work_keys_str_mv	AT qingchen prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT junliu prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT yanghe prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT liuyang prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT huiqiangluo prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT yixiwang prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT xuewenzhang prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy AT ningxiuli prevalenceofhbsagamongreproductiveagecouplesinchongqingapopulationbasedcrosssectionalstudy
_version_	1718374823421280256

Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.

Ejemplares similares