A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation

Immune cells are well equipped to eliminate invading bacteria, and one of their primary tools is the synthesis of bleach, hypochlorous acid (HOCl), the same chemical used as a household disinfectant. In this work, we present findings showing that many host-associated bacteria possess a bleach-sensi...

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Autores principales:	Arden Perkins, Dan A. Tudorica, Raphael D. Teixeira, Tilman Schirmer, Lindsay Zumwalt, O. Maduka Ogba, C. Keith Cassidy, Phillip J. Stansfeld, Karen Guillemin
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/552441f439374f9fbe0178df8f79fafe
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spelling	oai:doaj.org-article:552441f439374f9fbe0178df8f79fafe2021-11-03T21:15:02ZA Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation2150-751110.1128/mBio.00173-21https://doaj.org/article/552441f439374f9fbe0178df8f79fafe2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00173-21https://doaj.org/toc/2150-7511 Immune cells are well equipped to eliminate invading bacteria, and one of their primary tools is the synthesis of bleach, hypochlorous acid (HOCl), the same chemical used as a household disinfectant. In this work, we present findings showing that many host-associated bacteria possess a bleach-sensing protein that allows them to adapt to the presence of this chemical in their environment.Arden PerkinsDan A. TudoricaRaphael D. TeixeiraTilman SchirmerLindsay ZumwaltO. Maduka OgbaC. Keith CassidyPhillip J. StansfeldKaren GuilleminAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Arden Perkins Dan A. Tudorica Raphael D. Teixeira Tilman Schirmer Lindsay Zumwalt O. Maduka Ogba C. Keith Cassidy Phillip J. Stansfeld Karen Guillemin A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation
description	Immune cells are well equipped to eliminate invading bacteria, and one of their primary tools is the synthesis of bleach, hypochlorous acid (HOCl), the same chemical used as a household disinfectant. In this work, we present findings showing that many host-associated bacteria possess a bleach-sensing protein that allows them to adapt to the presence of this chemical in their environment.
format	article
author	Arden Perkins Dan A. Tudorica Raphael D. Teixeira Tilman Schirmer Lindsay Zumwalt O. Maduka Ogba C. Keith Cassidy Phillip J. Stansfeld Karen Guillemin
author_facet	Arden Perkins Dan A. Tudorica Raphael D. Teixeira Tilman Schirmer Lindsay Zumwalt O. Maduka Ogba C. Keith Cassidy Phillip J. Stansfeld Karen Guillemin
author_sort	Arden Perkins
title	A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation
title_short	A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation
title_full	A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation
title_fullStr	A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation
title_full_unstemmed	A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation
title_sort	bacterial inflammation sensor regulates c-di-gmp signaling, adhesion, and biofilm formation
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/552441f439374f9fbe0178df8f79fafe
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A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation

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