Genetic variants and increased expression of Parascaris equorum P-glycoprotein-11 in populations with decreased ivermectin susceptibility.

Macrocyclic lactones (MLs) represent the major drug class for control of parasitic infections in humans and animals. However, recently reports of treatment failures became more frequent. In addition to human and ruminant parasitic nematodes this also is the case for the horse-nematode Parascaris equ...

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Main Authors: I Jana I Janssen, Jürgen Krücken, Janina Demeler, Marta Basiaga, Sławomir Kornaś, Georg von Samson-Himmelstjerna
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/5527b4c5dff744fa935dbe565c2a65c2
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