Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization
Peck Lin Lip, Hemalatha Kolli, Dipti Trivedi Birmingham and Midland Eye Centre, Birmingham, UKCorrespondence: Peck Lin LipBirmingham and Midland Eye Centre Sandwell & West Birmingham NHS Trust City Hospital, Dudley Road, Birmingham B18 7QH, UKTel +44 121 5543801Fax +44 121 5076791Email pllip...
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Dove Medical Press
2020
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oai:doaj.org-article:552c249d670044258880458354b2006d2021-12-02T10:33:50ZUltra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization1177-5483https://doaj.org/article/552c249d670044258880458354b2006d2020-10-01T00:00:00Zhttps://www.dovepress.com/ultra-widefield-fluorescein-angiographic-patterns-retinal-microvascula-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Peck Lin Lip, Hemalatha Kolli, Dipti Trivedi Birmingham and Midland Eye Centre, Birmingham, UKCorrespondence: Peck Lin LipBirmingham and Midland Eye Centre Sandwell & West Birmingham NHS Trust City Hospital, Dudley Road, Birmingham B18 7QH, UKTel +44 121 5543801Fax +44 121 5076791Email pllipwoo@gmail.comPurpose: To share the experience of using ultra-widefield fluorescein angiography (UWF-FA) in recognizing the potential signs for retinal neovascularizations (NVE) development in branch retinal vein occlusions (BRVO).Methods: Reporting angiographic findings in 60 BRVO eyes presenting with NVE and vitreous hemorrhage using UWF-FA investigation. Angiographic retinal ischemic index (ARI) was also calculated from UWF-FA as the ratio of digitally mapped ischemic retina area against area of optic disc, termed unit of disc diameter (DD).Results: We observed emerging angiographic features common to these patients: pattern of a localized non-perfused retina at early phase of UWF-FA remaining non-perfused at the late phase (black retinal ischemia, black-RI) (100%); presence of retinal microvascular anomalies (RMAs) at the “water-shed-border” of black-RI (100%); site of NVEs observed at either the same “water-shed-border” (42%) or from the main vessel branch within the black-RI (30%), or from both sites (28%); multiple NVEs were observed in all eyes except two with single active NVE. Median ARI size was 114 DD (SD 80 DD), range 5– 354 DD.Conclusion: We report a recurring angiographic pattern common to eyes with active BRVO-NVEs from UWF-FA, and NVEs in this clinical group can develop from varied ARI sizes. Further studies would be needed to establish the role of UWF-FA in predicting angiographic risk factors for BRVO-NVE.Keywords: definition, vitreous hemorrhage, ghost vessels, risk, laserLip PLKolli HTrivedi DDove Medical Pressarticlevitreous haemorrhageghost vesselsrisklaserOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 2965-2974 (2020) |
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vitreous haemorrhage ghost vessels risk laser Ophthalmology RE1-994 |
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vitreous haemorrhage ghost vessels risk laser Ophthalmology RE1-994 Lip PL Kolli H Trivedi D Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization |
description |
Peck Lin Lip, Hemalatha Kolli, Dipti Trivedi Birmingham and Midland Eye Centre, Birmingham, UKCorrespondence: Peck Lin LipBirmingham and Midland Eye Centre Sandwell & West Birmingham NHS Trust City Hospital, Dudley Road, Birmingham B18 7QH, UKTel +44 121 5543801Fax +44 121 5076791Email pllipwoo@gmail.comPurpose: To share the experience of using ultra-widefield fluorescein angiography (UWF-FA) in recognizing the potential signs for retinal neovascularizations (NVE) development in branch retinal vein occlusions (BRVO).Methods: Reporting angiographic findings in 60 BRVO eyes presenting with NVE and vitreous hemorrhage using UWF-FA investigation. Angiographic retinal ischemic index (ARI) was also calculated from UWF-FA as the ratio of digitally mapped ischemic retina area against area of optic disc, termed unit of disc diameter (DD).Results: We observed emerging angiographic features common to these patients: pattern of a localized non-perfused retina at early phase of UWF-FA remaining non-perfused at the late phase (black retinal ischemia, black-RI) (100%); presence of retinal microvascular anomalies (RMAs) at the “water-shed-border” of black-RI (100%); site of NVEs observed at either the same “water-shed-border” (42%) or from the main vessel branch within the black-RI (30%), or from both sites (28%); multiple NVEs were observed in all eyes except two with single active NVE. Median ARI size was 114 DD (SD 80 DD), range 5– 354 DD.Conclusion: We report a recurring angiographic pattern common to eyes with active BRVO-NVEs from UWF-FA, and NVEs in this clinical group can develop from varied ARI sizes. Further studies would be needed to establish the role of UWF-FA in predicting angiographic risk factors for BRVO-NVE.Keywords: definition, vitreous hemorrhage, ghost vessels, risk, laser |
format |
article |
author |
Lip PL Kolli H Trivedi D |
author_facet |
Lip PL Kolli H Trivedi D |
author_sort |
Lip PL |
title |
Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization |
title_short |
Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization |
title_full |
Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization |
title_fullStr |
Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization |
title_full_unstemmed |
Ultra-Widefield Fluorescein Angiographic Patterns, Retinal Microvascular Anomalies and Retinal Ischemic Index in Branch Retinal Vein Occlusions with Established Retinal Neovascularization |
title_sort |
ultra-widefield fluorescein angiographic patterns, retinal microvascular anomalies and retinal ischemic index in branch retinal vein occlusions with established retinal neovascularization |
publisher |
Dove Medical Press |
publishDate |
2020 |
url |
https://doaj.org/article/552c249d670044258880458354b2006d |
work_keys_str_mv |
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