Specific age-associated DNA methylation changes in human dermal fibroblasts.

Specific age-associated DNA methylation changes in human dermal fibroblasts.

Epigenetic modifications of cytosine residues in the DNA play a critical role for cellular differentiation and potentially also for aging. In mesenchymal stromal cells (MSC) from human bone marrow we have previously demonstrated age-associated methylation changes at specific CpG-sites of development...

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Autores principales: Carmen M Koch, Christoph V Suschek, Qiong Lin, Simone Bork, Maria Goergens, Sylvia Joussen, Norbert Pallua, Anthony D Ho, Martin Zenke, Wolfgang Wagner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/552d19d59cd24deaa2c6dcc3df476c0e
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