Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest...
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EDP Sciences
2021
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oai:doaj.org-article:553bd2e850444cf6adf992303af778fc2021-11-08T15:17:40ZCacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts2117-445810.1051/bioconf/20213800073https://doaj.org/article/553bd2e850444cf6adf992303af778fc2021-01-01T00:00:00Zhttps://www.bio-conferences.org/articles/bioconf/pdf/2021/10/bioconf_napd2021_00073.pdfhttps://doaj.org/toc/2117-4458This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest). A log10 neutralization index—an indicator of inhibition of virus replication by the extract from C. hastata leaves—was ≤2 lg for each influenza virus. The extract reduced the infectivity of the human influenza virus by 1.5-fold and that of the avian influenza virus by 1.7-fold. The phytochemical characterization of C. hastata (its various organs) showed that the largest amount of the tested biologically active substances is present in leaves and rhizomes.Lobanova IrinaFilippova EkaterinaKotsupiy OlgaProtsenko MariaKharina TatianaMazurkova NataliaEDP SciencesarticleMicrobiologyQR1-502PhysiologyQP1-981ZoologyQL1-991ENFRBIO Web of Conferences, Vol 38, p 00073 (2021) |
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Microbiology QR1-502 Physiology QP1-981 Zoology QL1-991 |
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Microbiology QR1-502 Physiology QP1-981 Zoology QL1-991 Lobanova Irina Filippova Ekaterina Kotsupiy Olga Protsenko Maria Kharina Tatiana Mazurkova Natalia Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts |
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This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest). A log10 neutralization index—an indicator of inhibition of virus replication by the extract from C. hastata leaves—was ≤2 lg for each influenza virus. The extract reduced the infectivity of the human influenza virus by 1.5-fold and that of the avian influenza virus by 1.7-fold. The phytochemical characterization of C. hastata (its various organs) showed that the largest amount of the tested biologically active substances is present in leaves and rhizomes. |
format |
article |
author |
Lobanova Irina Filippova Ekaterina Kotsupiy Olga Protsenko Maria Kharina Tatiana Mazurkova Natalia |
author_facet |
Lobanova Irina Filippova Ekaterina Kotsupiy Olga Protsenko Maria Kharina Tatiana Mazurkova Natalia |
author_sort |
Lobanova Irina |
title |
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts |
title_short |
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts |
title_full |
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts |
title_fullStr |
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts |
title_full_unstemmed |
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts |
title_sort |
cacalia hastata l.: anti-influenza activity and phytochemical characteristics of extracts |
publisher |
EDP Sciences |
publishDate |
2021 |
url |
https://doaj.org/article/553bd2e850444cf6adf992303af778fc |
work_keys_str_mv |
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