Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts

This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest...

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Autores principales: Lobanova Irina, Filippova Ekaterina, Kotsupiy Olga, Protsenko Maria, Kharina Tatiana, Mazurkova Natalia
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Publicado: EDP Sciences 2021
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Acceso en línea:https://doaj.org/article/553bd2e850444cf6adf992303af778fc
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spelling oai:doaj.org-article:553bd2e850444cf6adf992303af778fc2021-11-08T15:17:40ZCacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts2117-445810.1051/bioconf/20213800073https://doaj.org/article/553bd2e850444cf6adf992303af778fc2021-01-01T00:00:00Zhttps://www.bio-conferences.org/articles/bioconf/pdf/2021/10/bioconf_napd2021_00073.pdfhttps://doaj.org/toc/2117-4458This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest). A log10 neutralization index—an indicator of inhibition of virus replication by the extract from C. hastata leaves—was ≤2 lg for each influenza virus. The extract reduced the infectivity of the human influenza virus by 1.5-fold and that of the avian influenza virus by 1.7-fold. The phytochemical characterization of C. hastata (its various organs) showed that the largest amount of the tested biologically active substances is present in leaves and rhizomes.Lobanova IrinaFilippova EkaterinaKotsupiy OlgaProtsenko MariaKharina TatianaMazurkova NataliaEDP SciencesarticleMicrobiologyQR1-502PhysiologyQP1-981ZoologyQL1-991ENFRBIO Web of Conferences, Vol 38, p 00073 (2021)
institution DOAJ
collection DOAJ
language EN
FR
topic Microbiology
QR1-502
Physiology
QP1-981
Zoology
QL1-991
spellingShingle Microbiology
QR1-502
Physiology
QP1-981
Zoology
QL1-991
Lobanova Irina
Filippova Ekaterina
Kotsupiy Olga
Protsenko Maria
Kharina Tatiana
Mazurkova Natalia
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
description This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest). A log10 neutralization index—an indicator of inhibition of virus replication by the extract from C. hastata leaves—was ≤2 lg for each influenza virus. The extract reduced the infectivity of the human influenza virus by 1.5-fold and that of the avian influenza virus by 1.7-fold. The phytochemical characterization of C. hastata (its various organs) showed that the largest amount of the tested biologically active substances is present in leaves and rhizomes.
format article
author Lobanova Irina
Filippova Ekaterina
Kotsupiy Olga
Protsenko Maria
Kharina Tatiana
Mazurkova Natalia
author_facet Lobanova Irina
Filippova Ekaterina
Kotsupiy Olga
Protsenko Maria
Kharina Tatiana
Mazurkova Natalia
author_sort Lobanova Irina
title Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
title_short Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
title_full Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
title_fullStr Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
title_full_unstemmed Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
title_sort cacalia hastata l.: anti-influenza activity and phytochemical characteristics of extracts
publisher EDP Sciences
publishDate 2021
url https://doaj.org/article/553bd2e850444cf6adf992303af778fc
work_keys_str_mv AT lobanovairina cacaliahastatalantiinfluenzaactivityandphytochemicalcharacteristicsofextracts
AT filippovaekaterina cacaliahastatalantiinfluenzaactivityandphytochemicalcharacteristicsofextracts
AT kotsupiyolga cacaliahastatalantiinfluenzaactivityandphytochemicalcharacteristicsofextracts
AT protsenkomaria cacaliahastatalantiinfluenzaactivityandphytochemicalcharacteristicsofextracts
AT kharinatatiana cacaliahastatalantiinfluenzaactivityandphytochemicalcharacteristicsofextracts
AT mazurkovanatalia cacaliahastatalantiinfluenzaactivityandphytochemicalcharacteristicsofextracts
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