Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment

Abstract Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurrin...

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Autores principales:	Catherine Freeland, Rhea Racho, Maureen Kamischke, Kate Moraras, Evangeline Wang, Chari Cohen, Stuart Kendrick
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Hepatitis B Virus (HBV) Health related quality of life (HRQL) Patient reported outcomes (PRO) Viral hepatitis Liver disease Liver cancer Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/554aec1c79554416ae1a4603253b9d00
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spelling	oai:doaj.org-article:554aec1c79554416ae1a4603253b9d002021-11-14T12:28:56ZHealth-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment10.1186/s41687-021-00398-82509-8020https://doaj.org/article/554aec1c79554416ae1a4603253b9d002021-11-01T00:00:00Zhttps://doi.org/10.1186/s41687-021-00398-8https://doaj.org/toc/2509-8020Abstract Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurring. The aim of this study was to explore the working conceptual framework of health related quality of life (HRQL) for those living with chronic HBV through qualitative analysis. Methods Data were collected by in-depth telephone interviews conducted in 2019 using purposeful sampling as part of a disease understanding assessment on the HBV patient experience within the United States. A directed content analysis approach was utilized by creation of a codebook to guide the organization of data, codes were developed by review of the literature (a priori) and through line-by-line reading of a subsample of queries. All transcripts were analyzed by at least two members of the study team and intercoder reliability was assessed using Dedoose software. Findings A sample of 19 individuals living with chronic HBV were included within this study. Themes identified from transcripts noted the significant overlap between the reported experience of HBV and constructs within the HRQL model. The psychological impact of chronic HBV on study participants’ HRQL overall was considerable and contributed to depression, anxiety, homelessness, drug use, and incarceration. Conclusion Our analysis supports the hypothesis that HBV impacts HRQL and often negatively affects emotional health. Our findings suggest that it would be beneficial to include HRQL assessment in the medical management of HBV, so that interventions can focus on reducing the burden of disease and improving quality of life for those living with HBV.Catherine FreelandRhea RachoMaureen KamischkeKate MorarasEvangeline WangChari CohenStuart KendrickSpringerOpenarticleHepatitis B Virus (HBV)Health related quality of life (HRQL)Patient reported outcomes (PRO)Viral hepatitisLiver diseaseLiver cancerPublic aspects of medicineRA1-1270ENJournal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hepatitis B Virus (HBV) Health related quality of life (HRQL) Patient reported outcomes (PRO) Viral hepatitis Liver disease Liver cancer Public aspects of medicine RA1-1270
spellingShingle	Hepatitis B Virus (HBV) Health related quality of life (HRQL) Patient reported outcomes (PRO) Viral hepatitis Liver disease Liver cancer Public aspects of medicine RA1-1270 Catherine Freeland Rhea Racho Maureen Kamischke Kate Moraras Evangeline Wang Chari Cohen Stuart Kendrick Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
description	Abstract Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurring. The aim of this study was to explore the working conceptual framework of health related quality of life (HRQL) for those living with chronic HBV through qualitative analysis. Methods Data were collected by in-depth telephone interviews conducted in 2019 using purposeful sampling as part of a disease understanding assessment on the HBV patient experience within the United States. A directed content analysis approach was utilized by creation of a codebook to guide the organization of data, codes were developed by review of the literature (a priori) and through line-by-line reading of a subsample of queries. All transcripts were analyzed by at least two members of the study team and intercoder reliability was assessed using Dedoose software. Findings A sample of 19 individuals living with chronic HBV were included within this study. Themes identified from transcripts noted the significant overlap between the reported experience of HBV and constructs within the HRQL model. The psychological impact of chronic HBV on study participants’ HRQL overall was considerable and contributed to depression, anxiety, homelessness, drug use, and incarceration. Conclusion Our analysis supports the hypothesis that HBV impacts HRQL and often negatively affects emotional health. Our findings suggest that it would be beneficial to include HRQL assessment in the medical management of HBV, so that interventions can focus on reducing the burden of disease and improving quality of life for those living with HBV.
format	article
author	Catherine Freeland Rhea Racho Maureen Kamischke Kate Moraras Evangeline Wang Chari Cohen Stuart Kendrick
author_facet	Catherine Freeland Rhea Racho Maureen Kamischke Kate Moraras Evangeline Wang Chari Cohen Stuart Kendrick
author_sort	Catherine Freeland
title	Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_short	Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_full	Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_fullStr	Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_full_unstemmed	Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_sort	health-related quality of life for adults living with hepatitis b in the united states: a qualitative assessment
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/554aec1c79554416ae1a4603253b9d00
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Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment

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