Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment

Abstract Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurrin...

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Autores principales: Catherine Freeland, Rhea Racho, Maureen Kamischke, Kate Moraras, Evangeline Wang, Chari Cohen, Stuart Kendrick
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Lenguaje:EN
Publicado: SpringerOpen 2021
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Acceso en línea:https://doaj.org/article/554aec1c79554416ae1a4603253b9d00
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spelling oai:doaj.org-article:554aec1c79554416ae1a4603253b9d002021-11-14T12:28:56ZHealth-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment10.1186/s41687-021-00398-82509-8020https://doaj.org/article/554aec1c79554416ae1a4603253b9d002021-11-01T00:00:00Zhttps://doi.org/10.1186/s41687-021-00398-8https://doaj.org/toc/2509-8020Abstract Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurring. The aim of this study was to explore the working conceptual framework of health related quality of life (HRQL) for those living with chronic HBV through qualitative analysis. Methods Data were collected by in-depth telephone interviews conducted in 2019 using purposeful sampling as part of a disease understanding assessment on the HBV patient experience within the United States. A directed content analysis approach was utilized by creation of a codebook to guide the organization of data, codes were developed by review of the literature (a priori) and through line-by-line reading of a subsample of queries. All transcripts were analyzed by at least two members of the study team and intercoder reliability was assessed using Dedoose software. Findings A sample of 19 individuals living with chronic HBV were included within this study. Themes identified from transcripts noted the significant overlap between the reported experience of HBV and constructs within the HRQL model. The psychological impact of chronic HBV on study participants’ HRQL overall was considerable and contributed to depression, anxiety, homelessness, drug use, and incarceration. Conclusion Our analysis supports the hypothesis that HBV impacts HRQL and often negatively affects emotional health. Our findings suggest that it would be beneficial to include HRQL assessment in the medical management of HBV, so that interventions can focus on reducing the burden of disease and improving quality of life for those living with HBV.Catherine FreelandRhea RachoMaureen KamischkeKate MorarasEvangeline WangChari CohenStuart KendrickSpringerOpenarticleHepatitis B Virus (HBV)Health related quality of life (HRQL)Patient reported outcomes (PRO)Viral hepatitisLiver diseaseLiver cancerPublic aspects of medicineRA1-1270ENJournal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Hepatitis B Virus (HBV)
Health related quality of life (HRQL)
Patient reported outcomes (PRO)
Viral hepatitis
Liver disease
Liver cancer
Public aspects of medicine
RA1-1270
spellingShingle Hepatitis B Virus (HBV)
Health related quality of life (HRQL)
Patient reported outcomes (PRO)
Viral hepatitis
Liver disease
Liver cancer
Public aspects of medicine
RA1-1270
Catherine Freeland
Rhea Racho
Maureen Kamischke
Kate Moraras
Evangeline Wang
Chari Cohen
Stuart Kendrick
Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
description Abstract Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurring. The aim of this study was to explore the working conceptual framework of health related quality of life (HRQL) for those living with chronic HBV through qualitative analysis. Methods Data were collected by in-depth telephone interviews conducted in 2019 using purposeful sampling as part of a disease understanding assessment on the HBV patient experience within the United States. A directed content analysis approach was utilized by creation of a codebook to guide the organization of data, codes were developed by review of the literature (a priori) and through line-by-line reading of a subsample of queries. All transcripts were analyzed by at least two members of the study team and intercoder reliability was assessed using Dedoose software. Findings A sample of 19 individuals living with chronic HBV were included within this study. Themes identified from transcripts noted the significant overlap between the reported experience of HBV and constructs within the HRQL model. The psychological impact of chronic HBV on study participants’ HRQL overall was considerable and contributed to depression, anxiety, homelessness, drug use, and incarceration. Conclusion Our analysis supports the hypothesis that HBV impacts HRQL and often negatively affects emotional health. Our findings suggest that it would be beneficial to include HRQL assessment in the medical management of HBV, so that interventions can focus on reducing the burden of disease and improving quality of life for those living with HBV.
format article
author Catherine Freeland
Rhea Racho
Maureen Kamischke
Kate Moraras
Evangeline Wang
Chari Cohen
Stuart Kendrick
author_facet Catherine Freeland
Rhea Racho
Maureen Kamischke
Kate Moraras
Evangeline Wang
Chari Cohen
Stuart Kendrick
author_sort Catherine Freeland
title Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_short Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_full Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_fullStr Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_full_unstemmed Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment
title_sort health-related quality of life for adults living with hepatitis b in the united states: a qualitative assessment
publisher SpringerOpen
publishDate 2021
url https://doaj.org/article/554aec1c79554416ae1a4603253b9d00
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