Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk

Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk

Abnormal placentation is associated with recurrent spontaneous abortion (RSA) risk. Here the authors report that low embryonic villous succinate level associates with risk of RSA in patients, and increasing succinate levels is sufficient to reduce the incidence rate in a mouse model of spontaneous a...

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Autores principales: Xiao-Hui Wang, Sha Xu, Xiang-Yu Zhou, Rui Zhao, Yan Lin, Jing Cao, Wei-Dong Zang, Hui Tao, Wei Xu, Ming-Qing Li, Shi-Min Zhao, Li-Ping Jin, Jian-Yuan Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/554bcb641b204c6ea4a02f1be0c6e985
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spelling oai:doaj.org-article:554bcb641b204c6ea4a02f1be0c6e9852021-12-02T17:34:47ZLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk10.1038/s41467-021-23827-02041-1723https://doaj.org/article/554bcb641b204c6ea4a02f1be0c6e9852021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23827-0https://doaj.org/toc/2041-1723Abnormal placentation is associated with recurrent spontaneous abortion (RSA) risk. Here the authors report that low embryonic villous succinate level associates with risk of RSA in patients, and increasing succinate levels is sufficient to reduce the incidence rate in a mouse model of spontaneous abortion.Xiao-Hui WangSha XuXiang-Yu ZhouRui ZhaoYan LinJing CaoWei-Dong ZangHui TaoWei XuMing-Qing LiShi-Min ZhaoLi-Ping JinJian-Yuan ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiao-Hui Wang
Sha Xu
Xiang-Yu Zhou
Rui Zhao
Yan Lin
Jing Cao
Wei-Dong Zang
Hui Tao
Wei Xu
Ming-Qing Li
Shi-Min Zhao
Li-Ping Jin
Jian-Yuan Zhao
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
description Abnormal placentation is associated with recurrent spontaneous abortion (RSA) risk. Here the authors report that low embryonic villous succinate level associates with risk of RSA in patients, and increasing succinate levels is sufficient to reduce the incidence rate in a mouse model of spontaneous abortion.
format article
author Xiao-Hui Wang
Sha Xu
Xiang-Yu Zhou
Rui Zhao
Yan Lin
Jing Cao
Wei-Dong Zang
Hui Tao
Wei Xu
Ming-Qing Li
Shi-Min Zhao
Li-Ping Jin
Jian-Yuan Zhao
author_facet Xiao-Hui Wang
Sha Xu
Xiang-Yu Zhou
Rui Zhao
Yan Lin
Jing Cao
Wei-Dong Zang
Hui Tao
Wei Xu
Ming-Qing Li
Shi-Min Zhao
Li-Ping Jin
Jian-Yuan Zhao
author_sort Xiao-Hui Wang
title Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
title_short Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
title_full Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
title_fullStr Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
title_full_unstemmed Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
title_sort low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/554bcb641b204c6ea4a02f1be0c6e985
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