Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE

Abstract Similar to sampling perfection with application-optimized contrast using different flip angle evolutions (SPACE), T2-weighted fast field echo (FFE) also has a black blood effect and a high imaging efficiency. The purpose of this study was to optimize 3D_T2_FFE and compare it with 3D_T2_SPAC...

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Autores principales:	Ang Yang, Xue Hong Xiao, Zhi Long Wang, Yong Xin Zhang, Ke Yi Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/555b93aaeb33496abc41645e02f97143
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spelling	oai:doaj.org-article:555b93aaeb33496abc41645e02f971432021-12-02T13:57:25ZCarotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE10.1038/s41598-021-81309-12045-2322https://doaj.org/article/555b93aaeb33496abc41645e02f971432021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81309-1https://doaj.org/toc/2045-2322Abstract Similar to sampling perfection with application-optimized contrast using different flip angle evolutions (SPACE), T2-weighted fast field echo (FFE) also has a black blood effect and a high imaging efficiency. The purpose of this study was to optimize 3D_T2_FFE and compare it with 3D_T2_SPACE for carotid imaging. The scanning parameter of 3D_T2_FFE was optimized for the imaging of the carotid wall. Twenty healthy volunteers and 10 patients with carotid plaque underwent cervical 3D_T2_FFE and 3D_T2_SPACE examinations. The signal-to-noise ratios of the carotid wall (SNRwall) and lumen (SNRlumen), and the contrast-to-noise ratios between the wall and lumen (CNRwall_lumen) were compared. The incidence of the residual flow signal at the carotid bifurcation and the grades of flow voids in the cerebellopontine angle region in the two sequences were also compared. The reproducibility of the two sequences was tested. No significant difference was observed between the two sequences in terms of the SNRwall of healthy individuals and patients (P = 0.132 and 0.102, respectively). The SNRlumen in the 3D_T2_FFE images was lower than that in the 3D_T2_SPACE images. No significant difference was observed between the two sequences in terms of the CNRwall-lumen. The incidence of the residual flow signal at the carotid bifurcation in 3D_T2_FFE was significantly lower than that in 3D_T2_SPACE. The grades of flow suppression in the cerebellopontine angle region in 3D_T2_SPACE was lower than that in 3D_T2_FFE. Both sequences showed excellent inter-and intra-observer reproducibility. Compared to 3D_T2_SPACE, 3D_T2_FFE showed stronger flow suppression while maintaining good imaging quality, which can be used as an alternative tool for carotid imaging.Ang YangXue Hong XiaoZhi Long WangYong Xin ZhangKe Yi WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ang Yang Xue Hong Xiao Zhi Long Wang Yong Xin Zhang Ke Yi Wang Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE
description	Abstract Similar to sampling perfection with application-optimized contrast using different flip angle evolutions (SPACE), T2-weighted fast field echo (FFE) also has a black blood effect and a high imaging efficiency. The purpose of this study was to optimize 3D_T2_FFE and compare it with 3D_T2_SPACE for carotid imaging. The scanning parameter of 3D_T2_FFE was optimized for the imaging of the carotid wall. Twenty healthy volunteers and 10 patients with carotid plaque underwent cervical 3D_T2_FFE and 3D_T2_SPACE examinations. The signal-to-noise ratios of the carotid wall (SNRwall) and lumen (SNRlumen), and the contrast-to-noise ratios between the wall and lumen (CNRwall_lumen) were compared. The incidence of the residual flow signal at the carotid bifurcation and the grades of flow voids in the cerebellopontine angle region in the two sequences were also compared. The reproducibility of the two sequences was tested. No significant difference was observed between the two sequences in terms of the SNRwall of healthy individuals and patients (P = 0.132 and 0.102, respectively). The SNRlumen in the 3D_T2_FFE images was lower than that in the 3D_T2_SPACE images. No significant difference was observed between the two sequences in terms of the CNRwall-lumen. The incidence of the residual flow signal at the carotid bifurcation in 3D_T2_FFE was significantly lower than that in 3D_T2_SPACE. The grades of flow suppression in the cerebellopontine angle region in 3D_T2_SPACE was lower than that in 3D_T2_FFE. Both sequences showed excellent inter-and intra-observer reproducibility. Compared to 3D_T2_SPACE, 3D_T2_FFE showed stronger flow suppression while maintaining good imaging quality, which can be used as an alternative tool for carotid imaging.
format	article
author	Ang Yang Xue Hong Xiao Zhi Long Wang Yong Xin Zhang Ke Yi Wang
author_facet	Ang Yang Xue Hong Xiao Zhi Long Wang Yong Xin Zhang Ke Yi Wang
author_sort	Ang Yang
title	Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE
title_short	Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE
title_full	Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE
title_fullStr	Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE
title_full_unstemmed	Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE
title_sort	carotid wall imaging with 3d_t2_ffe: sequence parameter optimization and comparison with 3d_t2_space
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/555b93aaeb33496abc41645e02f97143
work_keys_str_mv	AT angyang carotidwallimagingwith3dt2ffesequenceparameteroptimizationandcomparisonwith3dt2space AT xuehongxiao carotidwallimagingwith3dt2ffesequenceparameteroptimizationandcomparisonwith3dt2space AT zhilongwang carotidwallimagingwith3dt2ffesequenceparameteroptimizationandcomparisonwith3dt2space AT yongxinzhang carotidwallimagingwith3dt2ffesequenceparameteroptimizationandcomparisonwith3dt2space AT keyiwang carotidwallimagingwith3dt2ffesequenceparameteroptimizationandcomparisonwith3dt2space
_version_	1718392321896087552

Carotid wall imaging with 3D_T2_FFE: sequence parameter optimization and comparison with 3D_T2_SPACE

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