Quantile-specific heritability of sibling leptin concentrations and its implications for gene-environment interactions
Abstract “Quantile-dependent expressivity” occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g., leptin) is high or low relative to its distribution. Leptin concentrations are strongly related to adiposity, whose heritability is quantile dependent. Whether inheri...
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2020
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| Accès en ligne: | https://doaj.org/article/555e4c01eac6454eb7af39bdb61283bc |
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