MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN

In this paper the microecological characteristics of Klebsiella spp. regional populations in the intestinal microbiota of infants were represented. 373 children (55,9 % of general quantity of researched) had disbiotic changes of intestinal microbiota related to increasing number of Klebsiella. The a...

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Autores principales:	E. V. Bukharova, S. M. Popkova, E. B. Rakova, Yu. P. Dzhioev, N. M. Shabanova, E. I. Ivanova, U. M. Nemchenko, M. V. Savelkaeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	intestinal microbiota disbiotic disorder antibiotic susceptibility phagosensitivity Science Q
Acceso en línea:	https://doaj.org/article/5563c620e70b4c4287e7e74081158a35
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spelling	oai:doaj.org-article:5563c620e70b4c4287e7e74081158a352021-11-23T06:14:26ZMICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN2541-94202587-9596https://doaj.org/article/5563c620e70b4c4287e7e74081158a352013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1453https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596In this paper the microecological characteristics of Klebsiella spp. regional populations in the intestinal microbiota of infants were represented. 373 children (55,9 % of general quantity of researched) had disbiotic changes of intestinal microbiota related to increasing number of Klebsiella. The autostrains sensitivity to antibiotic drugs (в-lactams, aminoglycosides, quinolones) and to purified Klebsiella pneumoniae phage and purified polyvalent Klebsiella phage were researched. Samples of isolates (n = 142) characterized by a high proportion of antibiotic susceptible strains. Phage sensitivity of bacteriophage to the commercial preparations was determined in 268 strains of Klebsiella spp. of two types (146 strains of K. Oxytoca and 122 strains of K. pneumonia). Probably high frequency of pathogens resistant to studied bacteriophages (K. oxytocain 66 % and K. pneumoniae in 77.8 % of cases) was the reason of low efficiency of phage therapy by specific phage and can explain high frequency of occurrence of Klebsiella at dysbiosis in children of early age.E. V. BukharovaS. M. PopkovaE. B. RakovaYu. P. DzhioevN. M. ShabanovaE. I. IvanovaU. M. NemchenkoM. V. SavelkaevaScientific Сentre for Family Health and Human Reproduction Problemsarticleintestinal microbiotadisbiotic disorderantibiotic susceptibilityphagosensitivityScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(2), Pp 93-96 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	intestinal microbiota disbiotic disorder antibiotic susceptibility phagosensitivity Science Q
spellingShingle	intestinal microbiota disbiotic disorder antibiotic susceptibility phagosensitivity Science Q E. V. Bukharova S. M. Popkova E. B. Rakova Yu. P. Dzhioev N. M. Shabanova E. I. Ivanova U. M. Nemchenko M. V. Savelkaeva MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN
description	In this paper the microecological characteristics of Klebsiella spp. regional populations in the intestinal microbiota of infants were represented. 373 children (55,9 % of general quantity of researched) had disbiotic changes of intestinal microbiota related to increasing number of Klebsiella. The autostrains sensitivity to antibiotic drugs (в-lactams, aminoglycosides, quinolones) and to purified Klebsiella pneumoniae phage and purified polyvalent Klebsiella phage were researched. Samples of isolates (n = 142) characterized by a high proportion of antibiotic susceptible strains. Phage sensitivity of bacteriophage to the commercial preparations was determined in 268 strains of Klebsiella spp. of two types (146 strains of K. Oxytoca and 122 strains of K. pneumonia). Probably high frequency of pathogens resistant to studied bacteriophages (K. oxytocain 66 % and K. pneumoniae in 77.8 % of cases) was the reason of low efficiency of phage therapy by specific phage and can explain high frequency of occurrence of Klebsiella at dysbiosis in children of early age.
format	article
author	E. V. Bukharova S. M. Popkova E. B. Rakova Yu. P. Dzhioev N. M. Shabanova E. I. Ivanova U. M. Nemchenko M. V. Savelkaeva
author_facet	E. V. Bukharova S. M. Popkova E. B. Rakova Yu. P. Dzhioev N. M. Shabanova E. I. Ivanova U. M. Nemchenko M. V. Savelkaeva
author_sort	E. V. Bukharova
title	MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN
title_short	MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN
title_full	MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN
title_fullStr	MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN
title_full_unstemmed	MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN
title_sort	microecological characteristics of klebsiella spp. regional populations in the intestinal microbiota of irkutsk children
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/5563c620e70b4c4287e7e74081158a35
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MICROECOLOGICAL CHARACTERISTICS OF KLEBSIELLA SPP. REGIONAL POPULATIONS IN THE INTESTINAL MICROBIOTA OF IRKUTSK CHILDREN

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