AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells
Abstract The study of primary glucagon-secreting α-cells is hampered by their low abundance and scattered distribution in rodent pancreatic islets. We have designed a double-stranded adeno-associated virus containing a rat proglucagon promoter (700 bp) driving enhanced green fluorescent protein (AAV...
Guardado en:
Autores principales: | Eva Tudurí, Maria M. Glavas, Ali Asadi, Robert K. Baker, Cara E. Ellis, Galina Soukhatcheva, Marjolaine Philit, Frank K. Huynh, James D. Johnson, C. Bruce Verchere, Timothy J. Kieffer |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/556a5308d1314702b2cd07d70fc68443 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Model for glucagon secretion by pancreatic α-cells.
por: Virginia González-Vélez, et al.
Publicado: (2012) -
α-cell glucokinase suppresses glucose-regulated glucagon secretion
por: Davide Basco, et al.
Publicado: (2018) -
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
por: Anna Edlund, et al.
Publicado: (2017) -
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
por: Elisa Vergari, et al.
Publicado: (2019) -
GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein
por: Ming Zhao, et al.
Publicado: (2021)