Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications

The impact of bacteriophages as antibacterial agents was known after their first discovery in 1915, and they were then employed to treat the bacterial infections. However, the discovery of penicillin in 1928 quickly overshadowed bacteriophage therapy, and paved the way for its large-scale production...

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Autor principal:	Ghadah A. Alsubhi
Formato:	article
Lenguaje:	EN
Publicado:	Ain Shams University 2021
Materias:	bacteriophages phage therapy phage therapy limitations Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/556e9bc460ba425cba8f45cede45d693
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spelling	oai:doaj.org-article:556e9bc460ba425cba8f45cede45d6932021-11-15T10:45:52ZBacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications 10.21608/nrmj.2021.2047982537-02862537-0294https://doaj.org/article/556e9bc460ba425cba8f45cede45d6932021-11-01T00:00:00Zhttps://nrmj.journals.ekb.eg/article_204798_7cd08a33a8f0d0204e8ecca9b4155008.pdfhttps://doaj.org/toc/2537-0286https://doaj.org/toc/2537-0294The impact of bacteriophages as antibacterial agents was known after their first discovery in 1915, and they were then employed to treat the bacterial infections. However, the discovery of penicillin in 1928 quickly overshadowed bacteriophage therapy, and paved the way for its large-scale production in the 1940s to enter the era of antibiotics. In recent years, resistant bacteria have contributed to increasing the studies on bacteriophages. A remarkable difference between phages and antibiotics is the remarkable phage's specificity to infect certain types of bacteria, which makes them excellent alternatives for treatment of the bacterial infections. Moreover, bacteriophages have different life cycles; knowing the differences between each cycle is essential to exploit the benefits of phages to humans. This review aimed to highlight the history of discovering the bacteriophages and their characteristics; discusses the numerous phages applications including phage therapy, and the limitations of their use. Ghadah A. AlsubhiAin Shams Universityarticlebacteriophagesphage therapyphage therapy limitationsMicrobiologyQR1-502ENNovel Research in Microbiology Journal, Vol 5, Iss 6, Pp 1405-1414 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bacteriophages phage therapy phage therapy limitations Microbiology QR1-502
spellingShingle	bacteriophages phage therapy phage therapy limitations Microbiology QR1-502 Ghadah A. Alsubhi Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
description	The impact of bacteriophages as antibacterial agents was known after their first discovery in 1915, and they were then employed to treat the bacterial infections. However, the discovery of penicillin in 1928 quickly overshadowed bacteriophage therapy, and paved the way for its large-scale production in the 1940s to enter the era of antibiotics. In recent years, resistant bacteria have contributed to increasing the studies on bacteriophages. A remarkable difference between phages and antibiotics is the remarkable phage's specificity to infect certain types of bacteria, which makes them excellent alternatives for treatment of the bacterial infections. Moreover, bacteriophages have different life cycles; knowing the differences between each cycle is essential to exploit the benefits of phages to humans. This review aimed to highlight the history of discovering the bacteriophages and their characteristics; discusses the numerous phages applications including phage therapy, and the limitations of their use.
format	article
author	Ghadah A. Alsubhi
author_facet	Ghadah A. Alsubhi
author_sort	Ghadah A. Alsubhi
title	Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
title_short	Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
title_full	Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
title_fullStr	Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
title_full_unstemmed	Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
title_sort	bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications
publisher	Ain Shams University
publishDate	2021
url	https://doaj.org/article/556e9bc460ba425cba8f45cede45d693
work_keys_str_mv	AT ghadahaalsubhi bacteriophagesasaffordablesolutionfortreatmentofmultidrugresistantbacteriaandtheirrecentpotentialapplications
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Bacteriophages as affordable solution for treatment of multidrug resistant bacteria, and their recent potential applications

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