Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer.
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Nature Portfolio
2018
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oai:doaj.org-article:5579f2342b364cb2902c5d7d5fcf3a262021-12-02T16:56:36ZMotor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane10.1038/s41467-018-06492-82041-1723https://doaj.org/article/5579f2342b364cb2902c5d7d5fcf3a262018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06492-8https://doaj.org/toc/2041-1723The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer.Alexander Benjamin SchendzielorzPiotr BragoszewskiNataliia NaumenkoRidhima GomkaleChristian SchulzBernard GuiardAgnieszka ChacinskaPeter RehlingNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Alexander Benjamin Schendzielorz Piotr Bragoszewski Nataliia Naumenko Ridhima Gomkale Christian Schulz Bernard Guiard Agnieszka Chacinska Peter Rehling Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane |
description |
The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer. |
format |
article |
author |
Alexander Benjamin Schendzielorz Piotr Bragoszewski Nataliia Naumenko Ridhima Gomkale Christian Schulz Bernard Guiard Agnieszka Chacinska Peter Rehling |
author_facet |
Alexander Benjamin Schendzielorz Piotr Bragoszewski Nataliia Naumenko Ridhima Gomkale Christian Schulz Bernard Guiard Agnieszka Chacinska Peter Rehling |
author_sort |
Alexander Benjamin Schendzielorz |
title |
Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane |
title_short |
Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane |
title_full |
Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane |
title_fullStr |
Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane |
title_full_unstemmed |
Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane |
title_sort |
motor recruitment to the tim23 channel’s lateral gate restricts polypeptide release into the inner membrane |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/5579f2342b364cb2902c5d7d5fcf3a26 |
work_keys_str_mv |
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1718382800637263872 |