Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer.

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Autores principales: Alexander Benjamin Schendzielorz, Piotr Bragoszewski, Nataliia Naumenko, Ridhima Gomkale, Christian Schulz, Bernard Guiard, Agnieszka Chacinska, Peter Rehling
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5579f2342b364cb2902c5d7d5fcf3a26
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spelling oai:doaj.org-article:5579f2342b364cb2902c5d7d5fcf3a262021-12-02T16:56:36ZMotor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane10.1038/s41467-018-06492-82041-1723https://doaj.org/article/5579f2342b364cb2902c5d7d5fcf3a262018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06492-8https://doaj.org/toc/2041-1723The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer.Alexander Benjamin SchendzielorzPiotr BragoszewskiNataliia NaumenkoRidhima GomkaleChristian SchulzBernard GuiardAgnieszka ChacinskaPeter RehlingNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander Benjamin Schendzielorz
Piotr Bragoszewski
Nataliia Naumenko
Ridhima Gomkale
Christian Schulz
Bernard Guiard
Agnieszka Chacinska
Peter Rehling
Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
description The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane. Here authors show that the import motor J-protein Pam18 controls lateral protein release into the lipid bilayer.
format article
author Alexander Benjamin Schendzielorz
Piotr Bragoszewski
Nataliia Naumenko
Ridhima Gomkale
Christian Schulz
Bernard Guiard
Agnieszka Chacinska
Peter Rehling
author_facet Alexander Benjamin Schendzielorz
Piotr Bragoszewski
Nataliia Naumenko
Ridhima Gomkale
Christian Schulz
Bernard Guiard
Agnieszka Chacinska
Peter Rehling
author_sort Alexander Benjamin Schendzielorz
title Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
title_short Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
title_full Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
title_fullStr Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
title_full_unstemmed Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane
title_sort motor recruitment to the tim23 channel’s lateral gate restricts polypeptide release into the inner membrane
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5579f2342b364cb2902c5d7d5fcf3a26
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