Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test

Identification of febrile children at risk of death in low-resource settings can improve survival, but tools for their prompt recognition are lacking. Here, the authors show that sTREM-1 measured at clinical presentation predicts in-hospital mortality in febrile children in Uganda.

Guardado en:
Detalles Bibliográficos
Autores principales: Aleksandra Leligdowicz, Andrea L. Conroy, Michael Hawkes, Melissa Richard-Greenblatt, Kathleen Zhong, Robert O. Opoka, Sophie Namasopo, David Bell, W. Conrad Liles, Bruno R. da Costa, Peter Jüni, Kevin C. Kain
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/5581a9756f0d416e88763e8d7283bcb5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:5581a9756f0d416e88763e8d7283bcb5
record_format dspace
spelling oai:doaj.org-article:5581a9756f0d416e88763e8d7283bcb52021-11-28T12:33:29ZRisk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test10.1038/s41467-021-27215-62041-1723https://doaj.org/article/5581a9756f0d416e88763e8d7283bcb52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27215-6https://doaj.org/toc/2041-1723Identification of febrile children at risk of death in low-resource settings can improve survival, but tools for their prompt recognition are lacking. Here, the authors show that sTREM-1 measured at clinical presentation predicts in-hospital mortality in febrile children in Uganda.Aleksandra LeligdowiczAndrea L. ConroyMichael HawkesMelissa Richard-GreenblattKathleen ZhongRobert O. OpokaSophie NamasopoDavid BellW. Conrad LilesBruno R. da CostaPeter JüniKevin C. KainNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aleksandra Leligdowicz
Andrea L. Conroy
Michael Hawkes
Melissa Richard-Greenblatt
Kathleen Zhong
Robert O. Opoka
Sophie Namasopo
David Bell
W. Conrad Liles
Bruno R. da Costa
Peter Jüni
Kevin C. Kain
Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
description Identification of febrile children at risk of death in low-resource settings can improve survival, but tools for their prompt recognition are lacking. Here, the authors show that sTREM-1 measured at clinical presentation predicts in-hospital mortality in febrile children in Uganda.
format article
author Aleksandra Leligdowicz
Andrea L. Conroy
Michael Hawkes
Melissa Richard-Greenblatt
Kathleen Zhong
Robert O. Opoka
Sophie Namasopo
David Bell
W. Conrad Liles
Bruno R. da Costa
Peter Jüni
Kevin C. Kain
author_facet Aleksandra Leligdowicz
Andrea L. Conroy
Michael Hawkes
Melissa Richard-Greenblatt
Kathleen Zhong
Robert O. Opoka
Sophie Namasopo
David Bell
W. Conrad Liles
Bruno R. da Costa
Peter Jüni
Kevin C. Kain
author_sort Aleksandra Leligdowicz
title Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
title_short Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
title_full Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
title_fullStr Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
title_full_unstemmed Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test
title_sort risk-stratification of febrile african children at risk of sepsis using strem-1 as basis for a rapid triage test
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5581a9756f0d416e88763e8d7283bcb5
work_keys_str_mv AT aleksandraleligdowicz riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT andrealconroy riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT michaelhawkes riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT melissarichardgreenblatt riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT kathleenzhong riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT robertoopoka riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT sophienamasopo riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT davidbell riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT wconradliles riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT brunordacosta riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT peterjuni riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
AT kevinckain riskstratificationoffebrileafricanchildrenatriskofsepsisusingstrem1asbasisforarapidtriagetest
_version_ 1718407890360860672