Eosinophils improve cardiac function after myocardial infarction

Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, cardiac fibroblast activation and fibrosis, and end...

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Autores principales: Jing Liu, Chongzhe Yang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Jie Li, Qin Huang, Conglin Liu, Yunzhe Wang, Dafeng Yang, Galina K. Sukhova, Jes S. Lindholt, Axel Diederichsen, Lars M. Rasmussen, Dazhu Li, Gail Newton, Francis W. Luscinskas, Lijun Liu, Peter Libby, Jing Wang, Junli Guo, Guo-Ping Shi
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/55842ce25e9141999c860602412da2fc
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spelling oai:doaj.org-article:55842ce25e9141999c860602412da2fc2021-12-02T13:24:15ZEosinophils improve cardiac function after myocardial infarction10.1038/s41467-020-19297-52041-1723https://doaj.org/article/55842ce25e9141999c860602412da2fc2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19297-5https://doaj.org/toc/2041-1723Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, cardiac fibroblast activation and fibrosis, and endothelium activation-mediated inflammatory cell accumulation.Jing LiuChongzhe YangTianxiao LiuZhiyong DengWenqian FangXian ZhangJie LiQin HuangConglin LiuYunzhe WangDafeng YangGalina K. SukhovaJes S. LindholtAxel DiederichsenLars M. RasmussenDazhu LiGail NewtonFrancis W. LuscinskasLijun LiuPeter LibbyJing WangJunli GuoGuo-Ping ShiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jing Liu
Chongzhe Yang
Tianxiao Liu
Zhiyong Deng
Wenqian Fang
Xian Zhang
Jie Li
Qin Huang
Conglin Liu
Yunzhe Wang
Dafeng Yang
Galina K. Sukhova
Jes S. Lindholt
Axel Diederichsen
Lars M. Rasmussen
Dazhu Li
Gail Newton
Francis W. Luscinskas
Lijun Liu
Peter Libby
Jing Wang
Junli Guo
Guo-Ping Shi
Eosinophils improve cardiac function after myocardial infarction
description Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, cardiac fibroblast activation and fibrosis, and endothelium activation-mediated inflammatory cell accumulation.
format article
author Jing Liu
Chongzhe Yang
Tianxiao Liu
Zhiyong Deng
Wenqian Fang
Xian Zhang
Jie Li
Qin Huang
Conglin Liu
Yunzhe Wang
Dafeng Yang
Galina K. Sukhova
Jes S. Lindholt
Axel Diederichsen
Lars M. Rasmussen
Dazhu Li
Gail Newton
Francis W. Luscinskas
Lijun Liu
Peter Libby
Jing Wang
Junli Guo
Guo-Ping Shi
author_facet Jing Liu
Chongzhe Yang
Tianxiao Liu
Zhiyong Deng
Wenqian Fang
Xian Zhang
Jie Li
Qin Huang
Conglin Liu
Yunzhe Wang
Dafeng Yang
Galina K. Sukhova
Jes S. Lindholt
Axel Diederichsen
Lars M. Rasmussen
Dazhu Li
Gail Newton
Francis W. Luscinskas
Lijun Liu
Peter Libby
Jing Wang
Junli Guo
Guo-Ping Shi
author_sort Jing Liu
title Eosinophils improve cardiac function after myocardial infarction
title_short Eosinophils improve cardiac function after myocardial infarction
title_full Eosinophils improve cardiac function after myocardial infarction
title_fullStr Eosinophils improve cardiac function after myocardial infarction
title_full_unstemmed Eosinophils improve cardiac function after myocardial infarction
title_sort eosinophils improve cardiac function after myocardial infarction
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/55842ce25e9141999c860602412da2fc
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