Eosinophils improve cardiac function after myocardial infarction
Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, cardiac fibroblast activation and fibrosis, and end...
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Nature Portfolio
2020
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oai:doaj.org-article:55842ce25e9141999c860602412da2fc2021-12-02T13:24:15ZEosinophils improve cardiac function after myocardial infarction10.1038/s41467-020-19297-52041-1723https://doaj.org/article/55842ce25e9141999c860602412da2fc2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19297-5https://doaj.org/toc/2041-1723Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, cardiac fibroblast activation and fibrosis, and endothelium activation-mediated inflammatory cell accumulation.Jing LiuChongzhe YangTianxiao LiuZhiyong DengWenqian FangXian ZhangJie LiQin HuangConglin LiuYunzhe WangDafeng YangGalina K. SukhovaJes S. LindholtAxel DiederichsenLars M. RasmussenDazhu LiGail NewtonFrancis W. LuscinskasLijun LiuPeter LibbyJing WangJunli GuoGuo-Ping ShiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q |
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Science Q Jing Liu Chongzhe Yang Tianxiao Liu Zhiyong Deng Wenqian Fang Xian Zhang Jie Li Qin Huang Conglin Liu Yunzhe Wang Dafeng Yang Galina K. Sukhova Jes S. Lindholt Axel Diederichsen Lars M. Rasmussen Dazhu Li Gail Newton Francis W. Luscinskas Lijun Liu Peter Libby Jing Wang Junli Guo Guo-Ping Shi Eosinophils improve cardiac function after myocardial infarction |
description |
Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, cardiac fibroblast activation and fibrosis, and endothelium activation-mediated inflammatory cell accumulation. |
format |
article |
author |
Jing Liu Chongzhe Yang Tianxiao Liu Zhiyong Deng Wenqian Fang Xian Zhang Jie Li Qin Huang Conglin Liu Yunzhe Wang Dafeng Yang Galina K. Sukhova Jes S. Lindholt Axel Diederichsen Lars M. Rasmussen Dazhu Li Gail Newton Francis W. Luscinskas Lijun Liu Peter Libby Jing Wang Junli Guo Guo-Ping Shi |
author_facet |
Jing Liu Chongzhe Yang Tianxiao Liu Zhiyong Deng Wenqian Fang Xian Zhang Jie Li Qin Huang Conglin Liu Yunzhe Wang Dafeng Yang Galina K. Sukhova Jes S. Lindholt Axel Diederichsen Lars M. Rasmussen Dazhu Li Gail Newton Francis W. Luscinskas Lijun Liu Peter Libby Jing Wang Junli Guo Guo-Ping Shi |
author_sort |
Jing Liu |
title |
Eosinophils improve cardiac function after myocardial infarction |
title_short |
Eosinophils improve cardiac function after myocardial infarction |
title_full |
Eosinophils improve cardiac function after myocardial infarction |
title_fullStr |
Eosinophils improve cardiac function after myocardial infarction |
title_full_unstemmed |
Eosinophils improve cardiac function after myocardial infarction |
title_sort |
eosinophils improve cardiac function after myocardial infarction |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/55842ce25e9141999c860602412da2fc |
work_keys_str_mv |
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