Eye-head coordination abnormalities in schizophrenia.

<h4>Background</h4>Eye-movement abnormalities in schizophrenia are a well-established phenomenon that has been observed in many studies. In such studies, visual targets are usually presented in the center of the visual field, and the subject's head remains fixed. However, in every-d...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Simon Schwab, Othmar Würmle, Nadja Razavi, René M Müri, Andreas Altorfer
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/558ef3c6897d473db91bee7c8f2d48b0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:558ef3c6897d473db91bee7c8f2d48b0
record_format	dspace
spelling	oai:doaj.org-article:558ef3c6897d473db91bee7c8f2d48b02021-11-18T08:55:57ZEye-head coordination abnormalities in schizophrenia.1932-620310.1371/journal.pone.0074845https://doaj.org/article/558ef3c6897d473db91bee7c8f2d48b02013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24040351/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Eye-movement abnormalities in schizophrenia are a well-established phenomenon that has been observed in many studies. In such studies, visual targets are usually presented in the center of the visual field, and the subject's head remains fixed. However, in every-day life, targets may also appear in the periphery. This study is among the first to investigate eye and head movements in schizophrenia by presenting targets in the periphery of the visual field.<h4>Methodology/principal findings</h4>Two different visual recognition tasks, color recognition and Landolt orientation tasks, were presented at the periphery (at a visual angle of 55° from the center of the field of view). Each subject viewed 96 trials, and all eye and head movements were simultaneously recorded using video-based oculography and magnetic motion tracking of the head. Data from 14 patients with schizophrenia and 14 controls were considered. The patients had similar saccadic latencies in both tasks, whereas controls had shorter saccadic latencies in the Landolt task. Patients performed more head movements, and had increased eye-head offsets during combined eye-head shifts than controls.<h4>Conclusions/significance</h4>Patients with schizophrenia may not be able to adapt to the two different tasks to the same extent as controls, as seen by the former's task-specific saccadic latency pattern. This can be interpreted as a specific oculomotoric attentional dysfunction and may support the hypothesis that schizophrenia patients have difficulties determining the relevance of stimuli. Patients may also show an uneconomic over-performance of head-movements, which is possibly caused by alterations in frontal executive function that impair the inhibition of head shifts. In addition, a model was created explaining 93% of the variance of the response times as a function of eye and head amplitude, which was only observed in the controls, indicating abnormal eye-head coordination in patients with schizophrenia.Simon SchwabOthmar WürmleNadja RazaviRené M MüriAndreas AltorferPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 9, p e74845 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Simon Schwab Othmar Würmle Nadja Razavi René M Müri Andreas Altorfer Eye-head coordination abnormalities in schizophrenia.
description	<h4>Background</h4>Eye-movement abnormalities in schizophrenia are a well-established phenomenon that has been observed in many studies. In such studies, visual targets are usually presented in the center of the visual field, and the subject's head remains fixed. However, in every-day life, targets may also appear in the periphery. This study is among the first to investigate eye and head movements in schizophrenia by presenting targets in the periphery of the visual field.<h4>Methodology/principal findings</h4>Two different visual recognition tasks, color recognition and Landolt orientation tasks, were presented at the periphery (at a visual angle of 55° from the center of the field of view). Each subject viewed 96 trials, and all eye and head movements were simultaneously recorded using video-based oculography and magnetic motion tracking of the head. Data from 14 patients with schizophrenia and 14 controls were considered. The patients had similar saccadic latencies in both tasks, whereas controls had shorter saccadic latencies in the Landolt task. Patients performed more head movements, and had increased eye-head offsets during combined eye-head shifts than controls.<h4>Conclusions/significance</h4>Patients with schizophrenia may not be able to adapt to the two different tasks to the same extent as controls, as seen by the former's task-specific saccadic latency pattern. This can be interpreted as a specific oculomotoric attentional dysfunction and may support the hypothesis that schizophrenia patients have difficulties determining the relevance of stimuli. Patients may also show an uneconomic over-performance of head-movements, which is possibly caused by alterations in frontal executive function that impair the inhibition of head shifts. In addition, a model was created explaining 93% of the variance of the response times as a function of eye and head amplitude, which was only observed in the controls, indicating abnormal eye-head coordination in patients with schizophrenia.
format	article
author	Simon Schwab Othmar Würmle Nadja Razavi René M Müri Andreas Altorfer
author_facet	Simon Schwab Othmar Würmle Nadja Razavi René M Müri Andreas Altorfer
author_sort	Simon Schwab
title	Eye-head coordination abnormalities in schizophrenia.
title_short	Eye-head coordination abnormalities in schizophrenia.
title_full	Eye-head coordination abnormalities in schizophrenia.
title_fullStr	Eye-head coordination abnormalities in schizophrenia.
title_full_unstemmed	Eye-head coordination abnormalities in schizophrenia.
title_sort	eye-head coordination abnormalities in schizophrenia.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/558ef3c6897d473db91bee7c8f2d48b0
work_keys_str_mv	AT simonschwab eyeheadcoordinationabnormalitiesinschizophrenia AT othmarwurmle eyeheadcoordinationabnormalitiesinschizophrenia AT nadjarazavi eyeheadcoordinationabnormalitiesinschizophrenia AT renemmuri eyeheadcoordinationabnormalitiesinschizophrenia AT andreasaltorfer eyeheadcoordinationabnormalitiesinschizophrenia
_version_	1718421141176975360

Eye-head coordination abnormalities in schizophrenia.

Ejemplares similares