Maturation of the human striatal dopamine system revealed by PET and quantitative MRI

Maturation of the human striatal dopamine system revealed by PET and quantitative MRI

How the human dopamine system changes during adolescence is still unclear. Here, the authors combine PET and quantitative MRI measures to show that dopamine D2/D3 receptor availability decreases with age while presynaptic dopamine vesicular storage was developmentally stable by age 18

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Autores principales: Bart Larsen, Valur Olafsson, Finnegan Calabro, Charles Laymon, Brenden Tervo-Clemmens, Elizabeth Campbell, Davneet Minhas, David Montez, Julie Price, Beatriz Luna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/558f3f172ed54c598928c89798f37901
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spelling oai:doaj.org-article:558f3f172ed54c598928c89798f379012021-12-02T16:56:49ZMaturation of the human striatal dopamine system revealed by PET and quantitative MRI10.1038/s41467-020-14693-32041-1723https://doaj.org/article/558f3f172ed54c598928c89798f379012020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14693-3https://doaj.org/toc/2041-1723How the human dopamine system changes during adolescence is still unclear. Here, the authors combine PET and quantitative MRI measures to show that dopamine D2/D3 receptor availability decreases with age while presynaptic dopamine vesicular storage was developmentally stable by age 18Bart LarsenValur OlafssonFinnegan CalabroCharles LaymonBrenden Tervo-ClemmensElizabeth CampbellDavneet MinhasDavid MontezJulie PriceBeatriz LunaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bart Larsen
Valur Olafsson
Finnegan Calabro
Charles Laymon
Brenden Tervo-Clemmens
Elizabeth Campbell
Davneet Minhas
David Montez
Julie Price
Beatriz Luna
Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
description How the human dopamine system changes during adolescence is still unclear. Here, the authors combine PET and quantitative MRI measures to show that dopamine D2/D3 receptor availability decreases with age while presynaptic dopamine vesicular storage was developmentally stable by age 18
format article
author Bart Larsen
Valur Olafsson
Finnegan Calabro
Charles Laymon
Brenden Tervo-Clemmens
Elizabeth Campbell
Davneet Minhas
David Montez
Julie Price
Beatriz Luna
author_facet Bart Larsen
Valur Olafsson
Finnegan Calabro
Charles Laymon
Brenden Tervo-Clemmens
Elizabeth Campbell
Davneet Minhas
David Montez
Julie Price
Beatriz Luna
author_sort Bart Larsen
title Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
title_short Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
title_full Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
title_fullStr Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
title_full_unstemmed Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
title_sort maturation of the human striatal dopamine system revealed by pet and quantitative mri
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/558f3f172ed54c598928c89798f37901
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