Leptin sensitizing effect of 1,3-butanediol and its potential mechanism

Abstract Leptin is an adipocyte-derived hormone that regulates appetite and energy expenditure via the hypothalamus. Since the majority of obese subjects are leptin resistant, leptin sensitizers, rather than leptin itself, are expected to be anti-obesity drugs. Endoplasmic reticulum (ER) stress in t...

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Autores principales: Masayo Isoda, Ken Ebihara, Nagisa Sawayama, Akiko Murakami, Chihiro Ebihara, Koji Shibuya, Akihito Takei, Shoko Takei, Tetsuji Wakabayashi, Daisuke Yamamuro, Manabu Takahashi, Shuichi Nagashima, Shun Ishibashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/55954b893e2a47f5a8684596d223f7c8
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