Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles

Currently, nanotechnology is gaining massive attention compared to conventional methods as the biosynthesis of plant-based nanoparticles is considered safe, effective, and ecofriendly. Therefore, keeping in view the importance of nanotechnology, the present study was designed to synthesize, characte...

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Autores principales:	Alhumaydhi Fahad A., Khan Ibrahim, Rauf Abdur, Qureshi Muhammad Nasimullah, Aljohani Abdullah S. M., Khan Shahid Ali, Khalil Anees Ahmed, El-Esawi Mohamed A, Muhammad Naveed
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	gold nanoparticles saffron (crocus sativus) flower stability of aunps catalytic degradation of dyes Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/559ada65d3654f3fb7e7cd3fb5b2fd17
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spelling	oai:doaj.org-article:559ada65d3654f3fb7e7cd3fb5b2fd172021-12-05T14:10:49ZSynthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles2191-955010.1515/gps-2021-0024https://doaj.org/article/559ada65d3654f3fb7e7cd3fb5b2fd172021-04-01T00:00:00Zhttps://doi.org/10.1515/gps-2021-0024https://doaj.org/toc/2191-9550Currently, nanotechnology is gaining massive attention compared to conventional methods as the biosynthesis of plant-based nanoparticles is considered safe, effective, and ecofriendly. Therefore, keeping in view the importance of nanotechnology, the present study was designed to synthesize, characterize, and evaluate the biological effectiveness of saffron stigma-based gold nanoparticles (SS-AuNPs) for their in vitro and in vivo biological properties. These gold nanoparticles were characterized by UV–Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD). The highest antibacterial effect was observed by the saffron extract against Escherichia coli (22 mm). SS-AuNPs significantly inhibited the activity of enzyme urease (54.98%) and CA-II (64.29%). However, the nonsignificant inhibitory effect was observed in the case of α-chymotrypsin. Maximum analgesic (84.98%) and antiinflammatory (88.98%) effects were observed for SS-AuNPs (10 mg/kg). Similarly, SS-AuNPs demonstrated a significant (P < 0.01) sedative effect at all tested doses.Alhumaydhi Fahad A.Khan IbrahimRauf AbdurQureshi Muhammad NasimullahAljohani Abdullah S. M.Khan Shahid AliKhalil Anees AhmedEl-Esawi Mohamed AMuhammad NaveedDe Gruyterarticlegold nanoparticlessaffron (crocus sativus) flowerstability of aunpscatalytic degradation of dyesChemistryQD1-999ENGreen Processing and Synthesis, Vol 10, Iss 1, Pp 230-245 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	gold nanoparticles saffron (crocus sativus) flower stability of aunps catalytic degradation of dyes Chemistry QD1-999
spellingShingle	gold nanoparticles saffron (crocus sativus) flower stability of aunps catalytic degradation of dyes Chemistry QD1-999 Alhumaydhi Fahad A. Khan Ibrahim Rauf Abdur Qureshi Muhammad Nasimullah Aljohani Abdullah S. M. Khan Shahid Ali Khalil Anees Ahmed El-Esawi Mohamed A Muhammad Naveed Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles
description	Currently, nanotechnology is gaining massive attention compared to conventional methods as the biosynthesis of plant-based nanoparticles is considered safe, effective, and ecofriendly. Therefore, keeping in view the importance of nanotechnology, the present study was designed to synthesize, characterize, and evaluate the biological effectiveness of saffron stigma-based gold nanoparticles (SS-AuNPs) for their in vitro and in vivo biological properties. These gold nanoparticles were characterized by UV–Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD). The highest antibacterial effect was observed by the saffron extract against Escherichia coli (22 mm). SS-AuNPs significantly inhibited the activity of enzyme urease (54.98%) and CA-II (64.29%). However, the nonsignificant inhibitory effect was observed in the case of α-chymotrypsin. Maximum analgesic (84.98%) and antiinflammatory (88.98%) effects were observed for SS-AuNPs (10 mg/kg). Similarly, SS-AuNPs demonstrated a significant (P < 0.01) sedative effect at all tested doses.
format	article
author	Alhumaydhi Fahad A. Khan Ibrahim Rauf Abdur Qureshi Muhammad Nasimullah Aljohani Abdullah S. M. Khan Shahid Ali Khalil Anees Ahmed El-Esawi Mohamed A Muhammad Naveed
author_facet	Alhumaydhi Fahad A. Khan Ibrahim Rauf Abdur Qureshi Muhammad Nasimullah Aljohani Abdullah S. M. Khan Shahid Ali Khalil Anees Ahmed El-Esawi Mohamed A Muhammad Naveed
author_sort	Alhumaydhi Fahad A.
title	Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles
title_short	Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles
title_full	Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles
title_fullStr	Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles
title_full_unstemmed	Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles
title_sort	synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (crocus sativus) flower stigma-based gold nanoparticles
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/559ada65d3654f3fb7e7cd3fb5b2fd17
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Synthesis, characterization, biological activities, and catalytic applications of alcoholic extract of saffron (Crocus sativus) flower stigma-based gold nanoparticles

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