Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation

BACKGROUND AND OBJECTIVE: Constipation is one of the most common disorders of gastrointestinal tract in children. Anorectal manometry (AM) is a non-invasive procedure to determine its etiology. The aim of this study was to present the findings of this diagnostic procedure and relationship between cl...

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Autores principales:	MR Esmaeili-Dooki, S Mehrabani Tabari, A Hadipour, A Bijani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2011
Materias:	children constipation manometry rectum Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/559c5c37385e4bce8d313afa8317012e
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spelling	oai:doaj.org-article:559c5c37385e4bce8d313afa8317012e2021-11-10T08:56:42ZAnorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation1561-41072251-7170https://doaj.org/article/559c5c37385e4bce8d313afa8317012e2011-07-01T00:00:00Zhttp://jbums.org/article-1-3844-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Constipation is one of the most common disorders of gastrointestinal tract in children. Anorectal manometry (AM) is a non-invasive procedure to determine its etiology. The aim of this study was to present the findings of this diagnostic procedure and relationship between clinical manifestations and determining the necessity of rectal biopsy. METHODS: This cross-sectional study was performed on 192 children with chronic constipation aged between 6 months to 12 years during 2008-2010 at Amirkola children’s hospital. For unresponsive cases to treatment, AM was performed. The association of fecal incontinency (FI) and withholding status, with recto anal inhibitory reflex (RAIR), internal anal sphincter tonicity (IAT) and necessity of rectal biopsy was analyzed.FINDINGS: The mean age of patients was 48.1±27.5 months. RAIR was present in 177 cases (92.2%) and absent in 15 cases (7.8%). The mean IAT was 34.1±19.9 cmH2O. All of the cases with history of FI were RAIR positive (p=0.04) and cases with history of withholding were RAIR positive too (p=0.607). Out of the 6 cases with rectal biopsy, in 4 patients Hirschsprung’s Disease (HD) was proved (2.08% of cases) that in these 4 cases, RAIR was not completely present.CONCLUSION: This study shows that although RAIR is present in the majority of severe chronic constipated patients, but HD is not ruled out specially in patients without FI and withholding and AM is beneficial in this specific group, for choosing them for probable rectal biopsy.MR Esmaeili-DookiS Mehrabani TabariA HadipourA BijaniBabol University of Medical SciencesarticlechildrenconstipationmanometryrectumMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 13, Iss 4, Pp 60-66 (2011)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	children constipation manometry rectum Medicine R Medicine (General) R5-920
spellingShingle	children constipation manometry rectum Medicine R Medicine (General) R5-920 MR Esmaeili-Dooki S Mehrabani Tabari A Hadipour A Bijani Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation
description	BACKGROUND AND OBJECTIVE: Constipation is one of the most common disorders of gastrointestinal tract in children. Anorectal manometry (AM) is a non-invasive procedure to determine its etiology. The aim of this study was to present the findings of this diagnostic procedure and relationship between clinical manifestations and determining the necessity of rectal biopsy. METHODS: This cross-sectional study was performed on 192 children with chronic constipation aged between 6 months to 12 years during 2008-2010 at Amirkola children’s hospital. For unresponsive cases to treatment, AM was performed. The association of fecal incontinency (FI) and withholding status, with recto anal inhibitory reflex (RAIR), internal anal sphincter tonicity (IAT) and necessity of rectal biopsy was analyzed.FINDINGS: The mean age of patients was 48.1±27.5 months. RAIR was present in 177 cases (92.2%) and absent in 15 cases (7.8%). The mean IAT was 34.1±19.9 cmH2O. All of the cases with history of FI were RAIR positive (p=0.04) and cases with history of withholding were RAIR positive too (p=0.607). Out of the 6 cases with rectal biopsy, in 4 patients Hirschsprung’s Disease (HD) was proved (2.08% of cases) that in these 4 cases, RAIR was not completely present.CONCLUSION: This study shows that although RAIR is present in the majority of severe chronic constipated patients, but HD is not ruled out specially in patients without FI and withholding and AM is beneficial in this specific group, for choosing them for probable rectal biopsy.
format	article
author	MR Esmaeili-Dooki S Mehrabani Tabari A Hadipour A Bijani
author_facet	MR Esmaeili-Dooki S Mehrabani Tabari A Hadipour A Bijani
author_sort	MR Esmaeili-Dooki
title	Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation
title_short	Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation
title_full	Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation
title_fullStr	Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation
title_full_unstemmed	Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation
title_sort	anorectal manometry as a tool to determine the necessity of rectal biopsy in children with severe chronic constipation
publisher	Babol University of Medical Sciences
publishDate	2011
url	https://doaj.org/article/559c5c37385e4bce8d313afa8317012e
work_keys_str_mv	AT mresmaeilidooki anorectalmanometryasatooltodeterminethenecessityofrectalbiopsyinchildrenwithseverechronicconstipation AT smehrabanitabari anorectalmanometryasatooltodeterminethenecessityofrectalbiopsyinchildrenwithseverechronicconstipation AT ahadipour anorectalmanometryasatooltodeterminethenecessityofrectalbiopsyinchildrenwithseverechronicconstipation AT abijani anorectalmanometryasatooltodeterminethenecessityofrectalbiopsyinchildrenwithseverechronicconstipation
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Anorectal Manometry as a Tool to Determine the Necessity of Rectal Biopsy in Children with Severe Chronic Constipation

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