Knockdown of Tlr4 in the Arcuate Nucleus Improves Obesity Related Metabolic Disorders

Abstract High-fat diet-induced hypothalamic metabolic inflammation is emerging as a cause for the development of obesity. It is acknowledged that Toll-like receptor4 (TLR4) signaling plays a crucial role in triggering of the hypothalamic metabolic inflammation during the course of diet-induced obesi...

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Auteurs principaux: Yongli Zhao, Guohua Li, Ying Li, Yuchuan Wang, Zhengjuan Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/55a383b6afce4a87959fa17f5371a1f8
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