Prevention and treatment of acute and chronic radiodermatitis

Sophie Seité,1 René-Jean Bensadoun,2 Jean-Michel Mazer3 1La Roche-Posay Laboratoire Dermatologique, Levallois-Perret, 2Centre de Haute Energie (CHE), Nice, 3Centre Laser International de la Peau, Paris, France Abstract: More than half the number of patients with cancer, who are...

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Autores principales:	Seité S, Bensadoun RJ, Mazer JM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Acute radiodermititis chronic radiodermatitis low level light therapy laser pulsed-dye prevention management skin care Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/55a63d654ae5450fb6f2019200e70474
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spelling	oai:doaj.org-article:55a63d654ae5450fb6f2019200e704742021-12-02T01:50:47ZPrevention and treatment of acute and chronic radiodermatitis1179-1314https://doaj.org/article/55a63d654ae5450fb6f2019200e704742017-11-01T00:00:00Zhttps://www.dovepress.com/prevention-and-treatment-of-acute-and-chronic-radiodermatitis-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Sophie Seité,1 René-Jean Bensadoun,2 Jean-Michel Mazer3 1La Roche-Posay Laboratoire Dermatologique, Levallois-Perret, 2Centre de Haute Energie (CHE), Nice, 3Centre Laser International de la Peau, Paris, France Abstract: More than half the number of patients with cancer, who are treated with radiotherapy, will have radiodermatitis at some point during their treatment. Radiodermatitis either occurs early on in the treatment period or appears months or up to several years later. Acute radiodermatitis is a burn injury that varies in severity according to both treatment and inherent patient factors. Most acute radiodermatitis reactions resolve after several weeks but some reactions persist and can cause complications. Late-onset radiodermatitis is characterized by telangiectasia that forms on atrophic and fragile skin. These radiodermatitis reactions can have a significant negative impact on concomitant and subsequent therapeutic protocols and most particularly on the patient’s quality of life. Today, treatment of radiodermatitis reactions is in its infancy. Although there is insufficient evidence available to form recommendations that would prevent or reduce radiodermatitis, some advances have been made using low level light therapy (LLLT) or vascular lasers to control the symptoms. Some recent preclinical and clinical research suggests that LLLT has biostimulating properties which allow the tissues to regenerate and heal faster, reduce inflammation, and prevent fibrosis. Also, in late-onset radiodermatitis pulsed dye laser treatment has been shown to be beneficial in clearing radiation-induced telangiectasia. In the absence of evidence-based recommendations, the objective of this paper is to review how to prevent or manage the symptoms of radiodermatitis reactions. Keywords: acute radiodermatitis, chronic radiodermatitis, low level light therapy, laser, pulsed dye, prevention, management, skin careSeité SBensadoun RJMazer JMDove Medical PressarticleAcute radiodermititischronic radiodermatitislow level light therapylaserpulsed-dyepreventionmanagementskin careNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol Volume 9, Pp 551-557 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Acute radiodermititis chronic radiodermatitis low level light therapy laser pulsed-dye prevention management skin care Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Acute radiodermititis chronic radiodermatitis low level light therapy laser pulsed-dye prevention management skin care Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Seité S Bensadoun RJ Mazer JM Prevention and treatment of acute and chronic radiodermatitis
description	Sophie Seité,1 René-Jean Bensadoun,2 Jean-Michel Mazer3 1La Roche-Posay Laboratoire Dermatologique, Levallois-Perret, 2Centre de Haute Energie (CHE), Nice, 3Centre Laser International de la Peau, Paris, France Abstract: More than half the number of patients with cancer, who are treated with radiotherapy, will have radiodermatitis at some point during their treatment. Radiodermatitis either occurs early on in the treatment period or appears months or up to several years later. Acute radiodermatitis is a burn injury that varies in severity according to both treatment and inherent patient factors. Most acute radiodermatitis reactions resolve after several weeks but some reactions persist and can cause complications. Late-onset radiodermatitis is characterized by telangiectasia that forms on atrophic and fragile skin. These radiodermatitis reactions can have a significant negative impact on concomitant and subsequent therapeutic protocols and most particularly on the patient’s quality of life. Today, treatment of radiodermatitis reactions is in its infancy. Although there is insufficient evidence available to form recommendations that would prevent or reduce radiodermatitis, some advances have been made using low level light therapy (LLLT) or vascular lasers to control the symptoms. Some recent preclinical and clinical research suggests that LLLT has biostimulating properties which allow the tissues to regenerate and heal faster, reduce inflammation, and prevent fibrosis. Also, in late-onset radiodermatitis pulsed dye laser treatment has been shown to be beneficial in clearing radiation-induced telangiectasia. In the absence of evidence-based recommendations, the objective of this paper is to review how to prevent or manage the symptoms of radiodermatitis reactions. Keywords: acute radiodermatitis, chronic radiodermatitis, low level light therapy, laser, pulsed dye, prevention, management, skin care
format	article
author	Seité S Bensadoun RJ Mazer JM
author_facet	Seité S Bensadoun RJ Mazer JM
author_sort	Seité S
title	Prevention and treatment of acute and chronic radiodermatitis
title_short	Prevention and treatment of acute and chronic radiodermatitis
title_full	Prevention and treatment of acute and chronic radiodermatitis
title_fullStr	Prevention and treatment of acute and chronic radiodermatitis
title_full_unstemmed	Prevention and treatment of acute and chronic radiodermatitis
title_sort	prevention and treatment of acute and chronic radiodermatitis
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/55a63d654ae5450fb6f2019200e70474
work_keys_str_mv	AT seites preventionandtreatmentofacuteandchronicradiodermatitis AT bensadounrj preventionandtreatmentofacuteandchronicradiodermatitis AT mazerjm preventionandtreatmentofacuteandchronicradiodermatitis
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Prevention and treatment of acute and chronic radiodermatitis

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