Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza

Abstract. Fitria R, Seno DSH, Priosoeryanto BP, Hartanti, Nurcholis W. 2019. Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza. Biodiversitas 20: 2943-2948. Cancer becomes one of the uncontagious diseases that occupy the top pos...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	RIZKI FITRIA, DJAROT SASONGKO HAMI SENO, BAMBANG PONTJO PRIOSOERYANTO, HARTANTI, Waras Nurcholis
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2019
Materias:	anticancer, curcuma aeruginosa, curcuma zanthorrhiza, essential oils, gc-ms Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/55ab6c393e8f4c16a3bce361fc4dca69
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:55ab6c393e8f4c16a3bce361fc4dca69
record_format	dspace
spelling	oai:doaj.org-article:55ab6c393e8f4c16a3bce361fc4dca692021-11-21T21:54:58ZVolatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza1412-033X2085-472210.13057/biodiv/d201024https://doaj.org/article/55ab6c393e8f4c16a3bce361fc4dca692019-09-01T00:00:00Zhttps://smujo.id/biodiv/article/view/4291https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Fitria R, Seno DSH, Priosoeryanto BP, Hartanti, Nurcholis W. 2019. Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza. Biodiversitas 20: 2943-2948. Cancer becomes one of the uncontagious diseases that occupy the top position in the cause of human death under 70 years in the world. Breast cancer is the most widely experienced cancer by women. The aim of this study was to obtain cytotoxic activity essential oil of Curcuma aeruginosa and Curcuma zanthorrhiza as antiproliferative substance of cancer cells and to analyze volatile profile of C. aeruginosa and C. zanthorrhiza essential oils. The essential oils were obtained from rhizomes of C. aeruginosa and C. zanthorrhiza by using hydrodistillation method. Volatile compositions of essential oils were analyzed using gas chromatography and mass spectrophotometry (GC/MS). The cytotoxic activities of the essential oil samples were evaluated using brine shrimp lethality test and against MCF-7 (Michigan Cancer Foundation-7) and Vero cells. The essential oils of C. aeruginosa, and C. zanthorrhiza showed cytotoxic activities to brine shrimp and MCF-7. Cytotoxic activity presented in essential oil from C. aeruginosa and C. zanthorrhiza showed lower activity compared with Doxorubicin. The major compounds of C. aeruginosa were tropolone (18.1%), eucalyptol (17.9%), and curcumol (5.7%), whereas C. zanthorrhiza were xanthorrhizol (26.8%), b-curcumene (17.0%), ar-curcumene (15.0%), and germacrone (5.4%).RIZKI FITRIADJAROT SASONGKO HAMI SENOBAMBANG PONTJO PRIOSOERYANTOHARTANTIWaras NurcholisMBI & UNS Soloarticleanticancer, curcuma aeruginosa, curcuma zanthorrhiza, essential oils, gc-msBiology (General)QH301-705.5ENBiodiversitas, Vol 20, Iss 10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	anticancer, curcuma aeruginosa, curcuma zanthorrhiza, essential oils, gc-ms Biology (General) QH301-705.5
spellingShingle	anticancer, curcuma aeruginosa, curcuma zanthorrhiza, essential oils, gc-ms Biology (General) QH301-705.5 RIZKI FITRIA DJAROT SASONGKO HAMI SENO BAMBANG PONTJO PRIOSOERYANTO HARTANTI Waras Nurcholis Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza
description	Abstract. Fitria R, Seno DSH, Priosoeryanto BP, Hartanti, Nurcholis W. 2019. Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza. Biodiversitas 20: 2943-2948. Cancer becomes one of the uncontagious diseases that occupy the top position in the cause of human death under 70 years in the world. Breast cancer is the most widely experienced cancer by women. The aim of this study was to obtain cytotoxic activity essential oil of Curcuma aeruginosa and Curcuma zanthorrhiza as antiproliferative substance of cancer cells and to analyze volatile profile of C. aeruginosa and C. zanthorrhiza essential oils. The essential oils were obtained from rhizomes of C. aeruginosa and C. zanthorrhiza by using hydrodistillation method. Volatile compositions of essential oils were analyzed using gas chromatography and mass spectrophotometry (GC/MS). The cytotoxic activities of the essential oil samples were evaluated using brine shrimp lethality test and against MCF-7 (Michigan Cancer Foundation-7) and Vero cells. The essential oils of C. aeruginosa, and C. zanthorrhiza showed cytotoxic activities to brine shrimp and MCF-7. Cytotoxic activity presented in essential oil from C. aeruginosa and C. zanthorrhiza showed lower activity compared with Doxorubicin. The major compounds of C. aeruginosa were tropolone (18.1%), eucalyptol (17.9%), and curcumol (5.7%), whereas C. zanthorrhiza were xanthorrhizol (26.8%), b-curcumene (17.0%), ar-curcumene (15.0%), and germacrone (5.4%).
format	article
author	RIZKI FITRIA DJAROT SASONGKO HAMI SENO BAMBANG PONTJO PRIOSOERYANTO HARTANTI Waras Nurcholis
author_facet	RIZKI FITRIA DJAROT SASONGKO HAMI SENO BAMBANG PONTJO PRIOSOERYANTO HARTANTI Waras Nurcholis
author_sort	RIZKI FITRIA
title	Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza
title_short	Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza
title_full	Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza
title_fullStr	Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza
title_full_unstemmed	Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza
title_sort	volatile compound profiles and cytotoxicity in essential oils from rhizome of curcuma aeruginosa and curcuma zanthorrhiza
publisher	MBI & UNS Solo
publishDate	2019
url	https://doaj.org/article/55ab6c393e8f4c16a3bce361fc4dca69
work_keys_str_mv	AT rizkifitria volatilecompoundprofilesandcytotoxicityinessentialoilsfromrhizomeofcurcumaaeruginosaandcurcumazanthorrhiza AT djarotsasongkohamiseno volatilecompoundprofilesandcytotoxicityinessentialoilsfromrhizomeofcurcumaaeruginosaandcurcumazanthorrhiza AT bambangpontjopriosoeryanto volatilecompoundprofilesandcytotoxicityinessentialoilsfromrhizomeofcurcumaaeruginosaandcurcumazanthorrhiza AT hartanti volatilecompoundprofilesandcytotoxicityinessentialoilsfromrhizomeofcurcumaaeruginosaandcurcumazanthorrhiza AT warasnurcholis volatilecompoundprofilesandcytotoxicityinessentialoilsfromrhizomeofcurcumaaeruginosaandcurcumazanthorrhiza
_version_	1718418642422464512

Volatile compound profiles and cytotoxicity in essential oils from rhizome of Curcuma aeruginosa and Curcuma zanthorrhiza

Ejemplares similares