An OB-fold complex controls the repair pathways for DNA double-strand breaks

An OB-fold complex controls the repair pathways for DNA double-strand breaks

How repair pathway selection occurs is still a matter of debate and many factors have been associated to this function. Here the authors provide insight into the role of FAM35A and C20ORF196, two REV7-interacting proteins, which are recruited at double-strand breaks to promote non-homologous end joi...

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Autores principales: Shengxian Gao, Sumin Feng, Shaokai Ning, Jingyan Liu, Huayu Zhao, Yixi Xu, Jinfeng Shang, Kejiao Li, Qing Li, Rong Guo, Dongyi Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/55ad8f7d27a64b04b08dc7e043796b6b
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spelling oai:doaj.org-article:55ad8f7d27a64b04b08dc7e043796b6b2021-12-02T15:34:05ZAn OB-fold complex controls the repair pathways for DNA double-strand breaks10.1038/s41467-018-06407-72041-1723https://doaj.org/article/55ad8f7d27a64b04b08dc7e043796b6b2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06407-7https://doaj.org/toc/2041-1723How repair pathway selection occurs is still a matter of debate and many factors have been associated to this function. Here the authors provide insight into the role of FAM35A and C20ORF196, two REV7-interacting proteins, which are recruited at double-strand breaks to promote non-homologous end joining repair.Shengxian GaoSumin FengShaokai NingJingyan LiuHuayu ZhaoYixi XuJinfeng ShangKejiao LiQing LiRong GuoDongyi XuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shengxian Gao
Sumin Feng
Shaokai Ning
Jingyan Liu
Huayu Zhao
Yixi Xu
Jinfeng Shang
Kejiao Li
Qing Li
Rong Guo
Dongyi Xu
An OB-fold complex controls the repair pathways for DNA double-strand breaks
description How repair pathway selection occurs is still a matter of debate and many factors have been associated to this function. Here the authors provide insight into the role of FAM35A and C20ORF196, two REV7-interacting proteins, which are recruited at double-strand breaks to promote non-homologous end joining repair.
format article
author Shengxian Gao
Sumin Feng
Shaokai Ning
Jingyan Liu
Huayu Zhao
Yixi Xu
Jinfeng Shang
Kejiao Li
Qing Li
Rong Guo
Dongyi Xu
author_facet Shengxian Gao
Sumin Feng
Shaokai Ning
Jingyan Liu
Huayu Zhao
Yixi Xu
Jinfeng Shang
Kejiao Li
Qing Li
Rong Guo
Dongyi Xu
author_sort Shengxian Gao
title An OB-fold complex controls the repair pathways for DNA double-strand breaks
title_short An OB-fold complex controls the repair pathways for DNA double-strand breaks
title_full An OB-fold complex controls the repair pathways for DNA double-strand breaks
title_fullStr An OB-fold complex controls the repair pathways for DNA double-strand breaks
title_full_unstemmed An OB-fold complex controls the repair pathways for DNA double-strand breaks
title_sort ob-fold complex controls the repair pathways for dna double-strand breaks
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/55ad8f7d27a64b04b08dc7e043796b6b
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