Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif

Mark Ultsch et al. report X-ray and NMR structures of the N-terminal domain of two closely related innate immunity proteins, ApoL1 and ApoL2. Their findings contribute to a better understanding of the ApoL immune protein family.

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Autores principales: Mark Ultsch, Michael J. Holliday, Stefan Gerhardy, Paul Moran, Suzie J. Scales, Nidhi Gupta, Francesca Oltrabella, Cecilia Chiu, Wayne Fairbrother, Charles Eigenbrot, Daniel Kirchhofer
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/55aec271b9224cfebb44d9647b2ae582
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spelling oai:doaj.org-article:55aec271b9224cfebb44d9647b2ae5822021-12-02T16:31:01ZStructures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif10.1038/s42003-021-02387-52399-3642https://doaj.org/article/55aec271b9224cfebb44d9647b2ae5822021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02387-5https://doaj.org/toc/2399-3642Mark Ultsch et al. report X-ray and NMR structures of the N-terminal domain of two closely related innate immunity proteins, ApoL1 and ApoL2. Their findings contribute to a better understanding of the ApoL immune protein family.Mark UltschMichael J. HollidayStefan GerhardyPaul MoranSuzie J. ScalesNidhi GuptaFrancesca OltrabellaCecilia ChiuWayne FairbrotherCharles EigenbrotDaniel KirchhoferNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mark Ultsch
Michael J. Holliday
Stefan Gerhardy
Paul Moran
Suzie J. Scales
Nidhi Gupta
Francesca Oltrabella
Cecilia Chiu
Wayne Fairbrother
Charles Eigenbrot
Daniel Kirchhofer
Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
description Mark Ultsch et al. report X-ray and NMR structures of the N-terminal domain of two closely related innate immunity proteins, ApoL1 and ApoL2. Their findings contribute to a better understanding of the ApoL immune protein family.
format article
author Mark Ultsch
Michael J. Holliday
Stefan Gerhardy
Paul Moran
Suzie J. Scales
Nidhi Gupta
Francesca Oltrabella
Cecilia Chiu
Wayne Fairbrother
Charles Eigenbrot
Daniel Kirchhofer
author_facet Mark Ultsch
Michael J. Holliday
Stefan Gerhardy
Paul Moran
Suzie J. Scales
Nidhi Gupta
Francesca Oltrabella
Cecilia Chiu
Wayne Fairbrother
Charles Eigenbrot
Daniel Kirchhofer
author_sort Mark Ultsch
title Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
title_short Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
title_full Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
title_fullStr Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
title_full_unstemmed Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
title_sort structures of the apol1 and apol2 n-terminal domains reveal a non-classical four-helix bundle motif
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/55aec271b9224cfebb44d9647b2ae582
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