Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α

Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α

Chromatin fibers undergo continuous structural rearrangements but their dynamic architecture is poorly understood. Here, the authors use single-molecule FRET to determine the structural states and interconversion kinetics of chromatin fibers, monitoring their effector protein-dependent dynamic motio...

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Autores principales: Sinan Kilic, Suren Felekyan, Olga Doroshenko, Iuliia Boichenko, Mykola Dimura, Hayk Vardanyan, Louise C. Bryan, Gaurav Arya, Claus A. M. Seidel, Beat Fierz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/55aef55e51994ac3bbeb3ecc70bf2209
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spelling oai:doaj.org-article:55aef55e51994ac3bbeb3ecc70bf22092021-12-02T14:40:09ZSingle-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α10.1038/s41467-017-02619-52041-1723https://doaj.org/article/55aef55e51994ac3bbeb3ecc70bf22092018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02619-5https://doaj.org/toc/2041-1723Chromatin fibers undergo continuous structural rearrangements but their dynamic architecture is poorly understood. Here, the authors use single-molecule FRET to determine the structural states and interconversion kinetics of chromatin fibers, monitoring their effector protein-dependent dynamic motions.Sinan KilicSuren FelekyanOlga DoroshenkoIuliia BoichenkoMykola DimuraHayk VardanyanLouise C. BryanGaurav AryaClaus A. M. SeidelBeat FierzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sinan Kilic
Suren Felekyan
Olga Doroshenko
Iuliia Boichenko
Mykola Dimura
Hayk Vardanyan
Louise C. Bryan
Gaurav Arya
Claus A. M. Seidel
Beat Fierz
Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
description Chromatin fibers undergo continuous structural rearrangements but their dynamic architecture is poorly understood. Here, the authors use single-molecule FRET to determine the structural states and interconversion kinetics of chromatin fibers, monitoring their effector protein-dependent dynamic motions.
format article
author Sinan Kilic
Suren Felekyan
Olga Doroshenko
Iuliia Boichenko
Mykola Dimura
Hayk Vardanyan
Louise C. Bryan
Gaurav Arya
Claus A. M. Seidel
Beat Fierz
author_facet Sinan Kilic
Suren Felekyan
Olga Doroshenko
Iuliia Boichenko
Mykola Dimura
Hayk Vardanyan
Louise C. Bryan
Gaurav Arya
Claus A. M. Seidel
Beat Fierz
author_sort Sinan Kilic
title Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
title_short Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
title_full Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
title_fullStr Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
title_full_unstemmed Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α
title_sort single-molecule fret reveals multiscale chromatin dynamics modulated by hp1α
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/55aef55e51994ac3bbeb3ecc70bf2209
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