Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities

In vitroassays involving multiple cell types cannot control the stoichiometry or contact times of cell-cell interactions. Here, the authors present a patterned co-culture platform based on printed oligonucleotides capable of controlling cell-cell interactions of up to four different cell types at th...

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Autores principales:	Sisi Chen, Andrew W. Bremer, Olivia J. Scheideler, Yun Suk Na, Michael E. Todhunter, Sonny Hsiao, Prithvi R. Bomdica, Michel M. Maharbiz, Zev J. Gartner, David V. Schaffer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/55b29f78522547ffa0cce3eafe375b99
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id	oai:doaj.org-article:55b29f78522547ffa0cce3eafe375b99
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spelling	oai:doaj.org-article:55b29f78522547ffa0cce3eafe375b992021-12-02T17:32:08ZInterrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities10.1038/ncomms103092041-1723https://doaj.org/article/55b29f78522547ffa0cce3eafe375b992016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10309https://doaj.org/toc/2041-1723In vitroassays involving multiple cell types cannot control the stoichiometry or contact times of cell-cell interactions. Here, the authors present a patterned co-culture platform based on printed oligonucleotides capable of controlling cell-cell interactions of up to four different cell types at the single-cell level.Sisi ChenAndrew W. BremerOlivia J. ScheidelerYun Suk NaMichael E. TodhunterSonny HsiaoPrithvi R. BomdicaMichel M. MaharbizZev J. GartnerDavid V. SchafferNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sisi Chen Andrew W. Bremer Olivia J. Scheideler Yun Suk Na Michael E. Todhunter Sonny Hsiao Prithvi R. Bomdica Michel M. Maharbiz Zev J. Gartner David V. Schaffer Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
description	In vitroassays involving multiple cell types cannot control the stoichiometry or contact times of cell-cell interactions. Here, the authors present a patterned co-culture platform based on printed oligonucleotides capable of controlling cell-cell interactions of up to four different cell types at the single-cell level.
format	article
author	Sisi Chen Andrew W. Bremer Olivia J. Scheideler Yun Suk Na Michael E. Todhunter Sonny Hsiao Prithvi R. Bomdica Michel M. Maharbiz Zev J. Gartner David V. Schaffer
author_facet	Sisi Chen Andrew W. Bremer Olivia J. Scheideler Yun Suk Na Michael E. Todhunter Sonny Hsiao Prithvi R. Bomdica Michel M. Maharbiz Zev J. Gartner David V. Schaffer
author_sort	Sisi Chen
title	Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
title_short	Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
title_full	Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
title_fullStr	Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
title_full_unstemmed	Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
title_sort	interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/55b29f78522547ffa0cce3eafe375b99
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Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities

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